BACKGROUND Human menopausal gonadotropin (hMG) has contributed many improvements to human assisted reproduction. However, effects of hMG on oocyte development and clinical results remain controversial. OBJECTIVE This study was conducted to investigate the effects of hMG on the zona pellucida of oocytes, as well as clinical results in superovulation treatment. MATERIALS AND METHODS This retr...

The effect of combined therapy with Wen-Jing-Tang and clomiphene citrate on anovulation was studied in 16 infertile patients who did not respond to clomiphene citrate alone. Wen-Jing-Tang was given at a dose of 5 g a day every day from day 2 of the menstrual cycles and clomiphene citrate was given at 150 mg a day for 5 days from day 5 of the cycle. Ovulation occurred in 43.8% of the patients an...

= Abstract = Follicular fluids and their matched oocytes were obtained from 16 follicles of 7 women who conceived after in vitro fertilization(IVF), and 49 follicles of 17 women who failed to conceive after the procedure. Follicular development was induced with a combination of follicle-stimulating hormone and human menopausal gonadotropin. There was no significant difference in follicular cycl...

background: leukemia inhibitory factor (lif) is a 45-56 kda glycoprotein that has an important role in proliferation and embryo implantation. its effect on oocyte maturation and how to exert the function remained to be elucidated. methods: immature mice superovulated with human menopausal gonadotropin and germinal vesicle (gv) oocytes were obtained from ovary 48 hours after. gv oocytes were cul...

objective(s) sildenafil citrate is a new drug and has special properties that bring about nitric oxide effects on vascular smooth muscle. the aim of this study was to assess the effects of ovarian stimulation and sildenafil citrate injection on pinopode expression in mice. materials and methods thirty adult female mice were randomly divided into three groups: control, hyperstimulated and hypers...

background: the purpose of this prospective randomized study was to compare ovarian response as well as oocytes embryo yields and pregnancy rates in women who underwent ovulation induction for intracytoplasmic sperm injection (icsi) with recombinant human fsh (rfsh) alone or in combination with human menopausal gonadotropin (hmg). materials and methods: out of 300 patients in assisted reproduct...

background: abnormal oocyte morphology has been associated with the hormonal environment to which the gametes are exposed. objective: in this study, we evaluated the oocytes morphology, fertilization rate, embryos quality, and implantation rate resulted of retrieved oocytes in different times after human chorionic gonadotrophin (hcg) administration. materials and methods: a total of 985 metapha...

abstract: introduction & objective: the infertility treatment by using in vitro matured oocyte has many potential applications. it minimizes the risk of ovarian hyper stimulation and is an alternative treatment for women with polycystic ovarian syndrome who may have problems regarding stimulation for ivf. this method may prove important for subjects in need of fertility preservation and also pr...