Globally, over 4% of the world population is affected by hepatitis C virus (HCV) infection. The current standard of care for hepatitis C infection is combination therapy with pegylated interferon and ribavirin for 48 weeks, which yield a sustained virological response in only a little over half of the patients with genotype 1 HCV. We investigated the clinical importance of pharmacogenetics in t...

UNLABELLED BECTS represents the vast majority of childhood focal epilepsy. Owing to the age peculiarity of children who suffer from this disease, i.e., school-going age of between 6 and 9 years, the condition is often referred to as a school disorder by parents and teachers. OBJECTIVE The aim of this study was to evaluate the academic performance of children with BECTS, according to the clini...

We report on the status of a set of ITPA-sponsored experiments among the Alcator C-Mod, MAST and NSTX devices to compare the characteristics and access conditions of small edge-localized modes (ELMs). Small ELM discharges were developed in each of the machines, and common features were identified, both in terms of ELM structure and operational windows. A common observation is an apparent βped t...

we have studied the changes in protein-protein interaction network of 38 different tissues of the human body. 123 gene expression samples from these tissues were used to construct human protein-protein interaction network. this network is then pruned using the gene expression samples of each tissue to construct different protein-protein interaction networks corresponding to different studied ti...

Introduction Juvenile idiopathic arthritis (JIA) is the most common arthritis disease of childhood and is an important cause of disability. Methotrexate (MTX) is the mainstay treatment in JIA. Unfortunately, 30-35% of patients fail to respond MTX, and the delay in identifying the optimal treatment at an early stage of disease can lead to longterm joint damage. Recent studies have evaluated comp...