today, the bidentate ligands 3-hydroxypyridin-4-ones (hpos) as orally active iron chelating agents have been demonstrated to possess potential for treatment of some human diseases such as iron-overload in thalassaemic patients and malaria. in this research, a series of hpos with different substitutes and position were theoretically invest

High-density magnetic storage or quantum computing could be achieved using small magnets with large magnetic anisotropy, a requirement that rare-earth iron alloys fulfill in bulk. This compelling property demands a thorough investigation of the magnetism in low dimensional rare-earth iron structures. Here, we report on the magnetic coupling between 4f single atoms and a 3d magnetic nanoisland. ...

Iron and oxygen share a delicate partnership since both are indispensable for survival, but if the partnership becomes inadequate, this may rapidly terminate life. Virtually all cell components are directly or indirectly affected by cellular iron metabolism, which represents a complex, redox-based machinery that is controlled by, and essential to, metabolic requirements. Under conditions of inc...

iron deficiency in soil reduces the quality of durum wheat leading to fe deficiency in human. thus, this experiment investigated the effects of foliar application of nano-iron oxide (2 and 4 g l-1), iron chelate (edta), (4 and 8 g l-1), iron sulfate (4 and 8 g l-1), and the control on grain yield and quality, yield components, chlorophyll and carotenoids contents, peroxidase (pox), catalase (ca...

Iron and ascorbate are vital cellular constituents in mammalian systems. The bulk-requirement for iron is during erythropoiesis leading to the generation of hemoglobin-containing erythrocytes. Additionally; both iron and ascorbate are required as co-factors in numerous metabolic reactions. Iron homeostasis is controlled at the level of uptake; rather than excretion. Accumulating evidence strong...

Nutritional iron deficiency anemia is the most common deficiency disorder, affecting more than two billion people worldwide. Oral iron supplementation is usually the first choice for the treatment of iron deficiency anemia, but in many conditions, oral iron is less than ideal mainly because of gastrointestinal adverse events and the long course needed to treat the disease and replenish body iro...

Introduction: In order to achieve sustainable development in mining, waste management is an essential requirement. The current study aimed to examine industrial solid waste produced in Golgohar Mining and Industrial Company, which is a well-known iron ore extraction and processing complex. Materials and Methods: This cross-sectional study was conducted in two phases from March, 2016 through Ma...

The importance of transferrin and iron for cell growth is well illustrated by the observation that proliferating cells in vitro have an absolute requirement for transferrin [l]. Although transferrin binds iron with a very high association constant (lo2' 121) cells are able to remove the iron and incorporate it into functional and storage compounds without degradation of the carrier protein. Aft...

Ferritin is an iron-storage protein composed of different ratios of 24 light (L) and heavy (H) subunits. The serum level of ferritin is a clinical marker of the body's iron level. Transferrin receptor (TFR)1 is the receptor not only for transferrin but also for H-ferritin, but how it binds two different ligands and the blood cell types that preferentially incorporate H-ferritin remain unknown. ...