Abstract Fascioliasis is a freshwater snail-borne zoonotic disease. The Northern Bolivian Altiplano very high altitude endemic area where the highest human prevalences and intensities have been reported. Preventive chemotherapy by treatment campaigns yearly applied. However, liver fluke infection of cattle, sheep, pigs donkeys assures endemicity consequent re-infection risks. A One Health actio...

ABSTRACT: Fascioliasis is a zoonosis of global distribution caused by the parasitic trematode Fasciola spp. Infection in humans can occur areas endemic for animal fascioliasis, suggesting need studies on this parasitosis and its determinants. This exploratory study aimed to analyze spatial bovine fascioliasis state Santa Catarina, Brazil, based cases notified between 2015 2017 abattoir, located...

Fasciola hepatica infestation is known to cause bile duct inflammation and biliary obstruction. Endoscopic retrograde cholangiopancreatography shows distinct features in some patients with fascioliasis, but the condition may be overlooked in chronic cases. The endoscopic retrograde cholangiopancreatograpy images must be carefully examined to rule out other possible causes of irregularity and th...

Fascioliasis is among important parasitic diseases which limit productivity of ruminants in particular cattle. Fasciola hepatica and Fasciola gigantica are the two liver flukes commonly reported to cause fascioliasis in ruminants. Fasciola hepatica may be acquired by man, but not directly from cattle. A person must ingest the metacercaria in order to become infected. The geographical distributi...

Cathepsin L1, a cysteine protease secreted by the gastrodermis of juvenile and adult Fasciola gigantica, was expressed in Escherichia coli as a calmodulin binding peptide fusion protein with a molecular mass of approximately 35 kD. The recombinant cathepsin L1 (rCTL1) was tested for its antigenic potential in a cystatin capture enzyme-linked immunosorbent assay (ELISA) to diagnose human fasciol...

Freshwater lymnaeid snails are crucial in defining transmission and epidemiology of fascioliasis. In South America, human endemic areas are related to high altitudes in Andean regions. The species Lymnaea diaphana has, however, been involved in low altitude areas of Chile, Argentina and Peru where human infection also occurs. Complete nuclear ribosomal DNA 18S, internal transcribed spacer (ITS)...

Fascioliasis due to Fasciola hepatica (Linnaeus, 1758) is an endemic disease on the Northern Bolivian Altiplano, where human prevalences and intensities are the highest known, sheep and cattle are the main reservoir hosts, and pigs and donkeys the secondary ones. Investigations were carried out to study the viability of metacercariae experimentally obtained from eggs shed by naturally infected ...