TiE relationship between changes in pressure and changes in volume within the eye is of practical importance in the calibration of tonometers and in tonographic calculations, and the coefficient of ocular rigidity, K, proposed by Friedenwald (1937) has been employed generally for these purposes. Contrary to Friedenwald's assertion, it has been found that this coefficient is not a constant, but ...

The human eye proteome is the latest addition to the HUPO Human Proteome Project (HPP). Semba et al. (The Human Eye Proteome Project: Perspectives on an emerging proteome. Proteomics 2013, 13, 2500-2511) establish a provisional baseline for the proteomes of the many anatomical compartments of the eye, based on literature review. As part of the Biology and Disease-driven HPP, they and their coll...

Human pigmentation, including eye color, has been associated with skin cancer risk. The P gene is the human homologue to the mouse pink-eye dilution locus and is responsible for oculocutaneous albinism type 2 and other phenotypes that confer eye hypopigmentation. The P gene is located on chromosome 15q11.2-q12, which is also the location of a putative eye pigmentation gene (EYCL3) inferred to e...

To the Editor: Researchers who wish to study human eye material sometimes experience severe difficulties in finding a source of tissue for their laboratory investigations. The recent formation of tissue procurement committees by the Retinitis Pigmentosa Foundation and the National Diabetes Research Interchange attests to the fact that those with special tissue requirements are preparing to meet...

In order to clarify the morphological uniqueness of the human eye and to obtain cues to understanding its adaptive significance, we compared the external morphology of the primate eye by measuring nearly half of all extant primate species. The results clearly showed exceptional features of the human eye: (1) the exposed white sclera is void of any pigmentation, (2) humans possess the largest ra...

Eye tracking has a long history in medical and psychological research as a tool for recording and studying human visual behavior. Real-time gaze-based text entry can also be a powerful means of communication and control for people with physical disabilities. Following recent technological advances and the advent of affordable eye trackers, there is a growing interest in pervasive attention-awar...

We describe a system for measuring the angle of eye gaze error on people with a squint. The program to analyse an eye image models each eye simply as a circular iris within a sphere rotating about its centre. A combination of edge detection, image transformation and template matching are then used to best fit the model to the image of the eye. The algorithm behaves correctly on 95% of eye image...