Objective: Danggui, the root of Angelica Sinensis, has traditionally been used for the treatment of women’s reproductive disorders in China for thousands of years. This study was to determine whether Danggui have potential anti-cancer effect on women’s cancer and its potential mechanism. Methods: Danggui was extracted by ethanol. The Cell Titer 96® Aqueous Non-Radioactive Cell Proliferation Ass...

Pro-environmental Behavior (PEB) yang diterapkan dalam kurikulum merupakan upaya percepatan perbaikan lingkungan. Melalui penelitian ini diharapkan mampu memberikan gambaran kategori PEB calon guru Fisika telah mendapatkan pembelajaran dengan terintegrasi PEB. Penelitian dilakukan menggunakan pendekatan kuantitatif, pengambilan sampel secara purposive sampling. Instrumen digunakan angket dua di...

To discover novel antimalarial and anticancer compounds, we carried out a genome analysis, bioassay, metabolite profiling, molecular docking of marine sediment actinobacteria strain GMY01. The whole-genome sequence analysis revealed that Streptomyces sp. GMY01 (7.9 Mbp) is most similar to sennicomposti RCPT1-4T with an average nucleotide identity (ANI) ANI based on BLAST+ (ANIb) values 98.09 97...

The growth of a panel of 22 different human tumor, leukemia, and lymphoma cell lines was examined in a human tumor cloning assay in agar or methylcellulose and a tritiated thymidine uptake assay. The cultures were performed in the absence or presence of increasing concentrations (0.5-500 ng/ml) of nerve growth factor (NGF). The growth of 17 of the 22 cell lines was not significantly and reprodu...

The efficiency of chemotherapy is often decreased by the development of resistance of cancer cells to cytostatic drugs. This phenomenon is in most cases caused by the activity of the various ABC transporters, multidrug-resistance (MDR) gene-encoded p-glycoproteins, that pump anticancer drugs out of the cells. The inhibition of the activities of the MDR proteins MDR1 and MRP was investigated via...

The objective of this study was to examine the effects of predictable vs. unpredictable management routines on the behaviour, production and health of dairy calves. Three different feeding schedules for milk-fed dairy calves were compared. All calves received milk twice a day, and had free access to concentrate, hay and water. Three groups of 12 calves (divided on two trials) were exposed to on...