The effect of spray drying on the different polyphenolic compounds present in root a purple-fleshed sweet potato variety Ipomoea batatas native from Peru was performed by HPLC-QTOF-MSMS. Nine anthocyanins, including four peonidin, three cyanidin and two pelargonidin derivatives glycosylated with sophorose and/or glucose acylated caffeic, ferulic p-hydroxybenzoic acid were identified. Twenty nin...

Complex extracts of rosemary honey constituents often require very effective separation techniques to allow the identification of different compounds. Capillary electrophoresis (CE) coupled to mass spectrometry (MS) detection can provide structure-selective information about the analytes in such matrices and has turned out to be an attractive alternative to HPLC methods. A simple and cost-effec...

Marginal structural models (MSMs) are becoming increasingly popular as a tool to make causal inference from longitudinal data. Unlike standard regression models, MSMs can adjust for time-dependent observed confounders while avoiding the bias due to the adjustment for covariates affected by the treatment. Despite their theoretical appeal, a main practical difficulty of MSMs is the required estim...

The HPLC system was equipped with a Waters XBridgeTM C18 column (2.1 × 150 mm, 5 μm), and the column temperature was set to 25 °C. The mobile phases for metabolic fingerprinting consisted of 0.1% formic acid in Milli-Q water and 5 mM ammonium acetate in Milli-Q water (solvent A, positive electrospray ionization (ESI+) and negative electrospray ionization (ESI–), respectively), acetonitrile (sol...

Apples (Malus domestica) are one of the most widely grown and consumed fruits in world that contain abundant phenolic compounds possess remarkable antioxidant potential. The current study characterised from five different varieties Australian apples (Royal Gala, Pink Lady, Red Delicious, Fuji Smitten) using LC-ESI-QTOF-MS/MS quantified through HPLC-PDA. content potential were determined various...

Phenolic compounds were extracted from defatted flaxseeds using ethanol-dioxane (1:1, v/v). The crude extract obtained was purified using Amberlite XAD-16 column chromatography with water and methanol as mobile phases. RP-HPLC and SE-HPLC showed a lignan macromolecule (LM) as a dominant phenolic compound in the purified extract. After the alkaline hydrolysis of LM caffeic acid glucoside (CaAG) ...

Amlodipine maleate is a maleate salt of 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate. An unknown impurity at m /z 392.2 for [M+H] ion has been detected during the accelerated stability analysis (40 °C /75 % RH) of amlodipine maleate drug substance by reverse-phase high performance liquid chromatography–mass spectrometry (RP-HPLC-MS)...