H olt-Oram syndrome (HOS) (MIM 142900), first described by Holt and Oram in 1960, is characterised by malformations of the upper limbs involving mainly the pre-axial ray and variable cardiac defects, most of them septation defects. This autosomal dominant inherited condition occurs in approximately 1 in 100 000 live births and shows high penetrative and variable intrafamilial and interfamilial ...

1. INTRODUCTION This paper is my description of the state of statistical data editing and current research problems. It is not intended to be a complete description of all areas. Rather, it represents sub-areas of statistical data editing that I will describe in sufficient detail so that the discussion of a few research problems is more easily understood. I define statistical data editing (SDE)...

In this article, we propose a generalized Beverton-Holt competition model subject to Allee effects and study its population dynamics to obtain insights on how the interplay of Allee effects and contest competition affects the persistence and the extinction of two competing species. By using the theory of monotone dynamics and the properties of critical curves for non-invertible maps, our analys...

Okihiro syndrome refers to the association of forearm malformations with Duane syndrome of eye retraction. Based on the reported literature experience, clinical diagnosis of the syndrome can be elusive, owing to the variable presentation in families reported. Specifically, there is overlap of clinical features with other conditions, most notably Holt-Oram syndrome, a condition resulting from mu...