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OBJECTIVE When the right atrium (RA) cannula is connected to the venous return line of the cardiopulmonary bypass (CPB) circuit, air is often introduced. Air in the venous cannula may increase cerebral air embolization at initiation of CPB despite the arterial line filter. We measured the volume of air present in the venous cannula after cannulation of the RA. Transcranial Doppler quantified em...
Internal HITs on Mechanical Turk can be programmatically restrictive, and as a result, many requesters turn to using external HITs as a more flexible alternative. However, creating such HITs can be redundant and timeconsuming. We present MmmTurkey, a framework that enables researchers to not only quickly create and manage external HITs, but more significantly also capture and record detailed wo...
We propose a method for detecting survey articles in a multilingual database. Generally, a survey article cites many important papers in a research domain. Using this feature, it is possible to detect survey articles. We applied HITS, which was devised to retrieve Web pages using the notions of authority and hub. We can consider that important papers and survey articles correspond to authoritie...
When it comes to structural biology, bigger really is better. Most biological processes are performed by enormous multicomponent complexes, such as the ribosome. To solve the structures of these monsters, biologists traditionally have used two different but complementary techniques, nuclear magnetic resonance (NMR) and X-ray crystallography. They have had considerable success using the latter t...
The objective of this study was to determine if surface-modifying additive (SMA) cardiopulmonary bypass (CPB) circuits are associated with a lower rate of cerebral microemboli during CPB compared with standard circuits. In a 2 x 2 factorial design, patients undergoing coronary artery bypass graft surgery were randomized to SMA or standard CPB circuits (with and without methyl-prednisolone). Tra...
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BACKGROUND AND PURPOSE Transcranial Doppler (TCD) can detect high-intensity transient signals (HITS) in the cerebral circulation. HITS may correspond to artifacts or solid or gaseous emboli. The aim of this study was to develop an offline automated Doppler system allowing the classification of HITS. METHODS We studied 600 HITS in vivo, including 200 artifacts from normal subjects, 200 solid e...
Transcranial Doppler-detected high-intensity transient signals (HITS) during cardiopulmonary bypass (CPB) surgery have been associated with postoperative neurocognitive dysfunction, suggesting microemboli in the brain could be a contributing factor. HITS occur despite administration of unfractionated heparin (UFH). This study was done to determine whether antithrombin-heparin covalent complex (...
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