Clinical and experimental studies have demonstrated some negative effect of hypertension on bone mineral density. The aim of this study was to evaluate bone healing and trabecular bone area (TBA) in spontaneously hypertensive rats (SHR), a well-established model of essential hypertension, when compared to normotensive rats (NTR). A critical-size defect was surgically created in the right tibia ...

Bone healing around titanium implants has already been evaluated; however, the effect of drugs such as calcitonin during the period of bone maturation around titanium implants has not yet been investigated. The purpose of this study was to evaluate the effects of calcitonin administration on the late period of bone healing following titanium implant insertion. Twenty-seven adult New Zealand rab...

BACKGROUND Enamel matrix-derived proteins (Emdogain) stimulate the proliferation of periodontal ligament cells, contributing to their regeneration. AIM This study was to perform histometric assessment of root surface resorption in replanted teeth with the use of Emdogain®. MATERIALS AND METHODS Male Wistar rats (Rattus norvegicus), weighing 180 to 200 gm, were anesthetized, subjected to ext...

The aim of the present study was to compare effects phenothiazine photosensitizers methylene blue (MB), toluidine blue-O (TBO) and butyl (BuTB) in antimicrobial photodynamic therapy (aPDT), as adjuvant scaling root planing (SRP) treatment experimental periodontitis (EP) rats. 120 Wistar rats underwent ligation around lower left molar. After seven days, ligature removed. animals were separated i...

The aim of this study was to evaluate, histometrically, the bone healing of the molar extraction socket just after cigarette smoke inhalation (CSI). Forty male Wistar rats were randomly assigned to a test group (animals exposed to CSI, starting 3 days before teeth extraction and maintained until sacrifice; n=20) and a control group (animals never exposed to CSI; n=20). Second mandibular molars ...