rhs work W U I c!onc 31 hila f h t f i n t c ~ i i ~ f i o r 1% us on \ahbuti<c,! system design and scheduling algorithm and avoiding poor or erroneous choices. The scheduling theory literature is so vast that we can’t pretend to be comprehensive, but this article does present a minimum set of results and their implications. The set includes Jackson’s rule, Smith’s rule, McNaughton’s theorem, L...

Inefficient secretion of the human coagulation factor (hFVIII) in mammalian expression systems is one ofthe main causes of the hFVIII low expression level, attributed to its interaction with a chaperone known asBiP/GRP78. In order to improve secretion efficiency of the hFVIII, based on the higher secretion level of theporcine FVIII and analysis of the hFVIII A110 region, that ...

Virulence factors generally enhance a pathogen's fitness and thereby foster transmission. However, most studies of pathogen fitness have been performed by averaging the phenotypes over large populations. Here, we have analyzed the fitness costs of virulence factor expression by Salmonella enterica subspecies I serovar Typhimurium in simple culture experiments. The type III secretion system ttss...

Salmonella enterica serovar Typhimurium (S. Typhimurium) is a major intestinal pathogen of both humans and animals. Salmonella pathogenicity island 1 (SPI-1)-encoded virulence genes are required for S. Typhimurium invasion. While oxygen (O2) limitation is an important signal for SPI-1 induction under host conditions, how the signal is received and integrated to the central SPI-1 regulatory syst...

Low threshold Ca2+ currents mediated by T-type channels underlie burst spike activities of relay neurons in the thalamus. We have previously reported that knock-out mice for T-type channels show an enhanced nociceptive response to visceral pain, accompanied by an increase in tonic spikes in the absence of burst spikes in thalamic relay neurons. These results raised a possibility that T-type cha...

During our dissection classes, we observed a lobulated spleen with multiple hila and fissures. The spleen presented 4 hila and 5 deep fissures. The hila were seen on the visceral surface. The fissures extended into the substance of the spleen from superior border, inferior border and the visceral surface. Because of these fissures, the spleen appeared to be lobulated, having seven distinct lobe...

Salmonella Typhimurium is attracting world wide attention as it continues to cause foodborne illness to human beings. The organism is resistant to a wide range of anti-infectious agents and as a result the illness is more difficult to treat. The objective of this study was to analyze the expression of specific virulence and stress genes (hilA and rpoS) in Salmonella Typhimurium at various nutri...

abstract in this study a greenhouse experiment was conducted to evaluate the role of acc deaminase enzyme on alleviation of salinity stress of canola plant. canola plants were exposed to pseudomonas fluorescens strain p12 which contains a rhizobacter capable of producing pseudomonas fluorescens in comparison with plants exposed to mutant pm12 unable to produce the required enzyme. the mutant wa...