BACKGROUND Manganese (Mn) used as raw material for melting process in the ferrous foundry is considered as hazardous neurotoxic substance because it accumulates in the central nervous system and may cause neurological disorders. The furnace-men and melting department workers are potentially exposed to manganese particles or fume in the workplace. The objective of the research has been to invest...

BACKGROUND Exposure to chemical mixtures is recognized as the real-life scenario in all populations, needing new statistical methods that can assess their complex effects. OBJECTIVES We aimed to assess the joint effect of in utero exposure to arsenic, manganese, and lead on children's neurodevelopment. METHODS We employed a novel statistical approach, Bayesian kernel machine regression (BKM...

Despite the importance of transition metals for normal brain function, relatively little is known about the distribution of these elemental species across the different tissue compartments of the primate brain. In this study, we employed laser ablation-inductively coupled plasma-mass spectrometry on PFA-fixed brain sections obtained from two adult common marmosets. Concurrent cytoarchitectonic,...

PURPOSE As the magnetic susceptibility induced frequency shift increases linearly with magnetic field strength, the present work evaluates manganese as a phase imaging contrast agent and investigates the dose dependence of brain enhancement in comparison to T(1) -weighted imaging after intravenous administration of MnCl(2). METHODS Experiments were carried out on 12 Sprague-Dawley rats. MnCl(...

Several cases of parkinsonism were found in a ferromanganese smelter after the ventilation system had broken down and had not been repaired for eight months in 1985. To determine the aetiology and prevalence of parkinsonism, 132 workers were submitted to thorough medical examination and estimated air concentrations of carbon monoxide and manganese at different worksites. Only six of eight worke...

To clarify whether manganese nutritional status is better reflected by the manganese concentration in lymphocytes or in whole blood, we injected manganese solutions intravenously into manganese-deficient rats and determined manganese concentrations in lymphocytes, whole blood, and various tissues. The manganese concentrations in lymphocytes and tissues, but not in whole blood, were significantl...

by MUSHTAQUE AHMAD, M.S. Washington State University December 2008 Chair: Richard J. Watts Oxidant interaction with subsurface materials is a major factor influencing the effective application of in situ chemical oxidation (ISCO) for contaminant destruction. The newest and least explored ISCO oxidant source is persulfate. Persulfate interaction with subsurface minerals was investigated as a bas...

Keratinocyte proliferation and migration are essential for the reconstruction of the cutaneous barrier after skin injury. Interestingly, thermal waters which are rich in trace elements (e.g. boron and manganese), are known to be able to improve wound healing. In order to understand the mechanism of action of this effect, our study investigated the in vitro modulation of keratinocyte migration a...

the low bioavailability of zinc (zn) is in calcareous and saline soil, therefore the study of chemical forms and bioavailability of zn in these soils is necessary to estimate the potential availability. the objective of this study was to evaluate the effect of plant growth promoting rhizobacteria and mycorrhizae fungi inoculation on the chemical forms of zn in a calcareous soil at different sal...

The aim of the study was to estimate the influence of soil pH on the uptake of copper, zinc, and manganese by Valeriana officinalis. Preliminary studies involved soil analyses to determine acidity, organic matter content, and copper, zinc, and manganese total and bioavailable forms. The study involved atomic absorption spectrometry to determine the concentration of the elements, and mineral soi...