An association between primary aldosteronism and metabolism disorders has been reported. The aim of this retrospective study was to test for this association by comparison between large cohorts of patients with primary aldosteronism and with essential hypertension. We retrieved the records of 460 cases with primary aldosteronism (103 lateralized, 150 not lateralized, and 207 undetermined) and o...

Objective(s) The purpose of the present study was to evaluate the effect of Ramadan fasting and weight-lifting training on plasma volume, glucose, and lipids profile of male weight-lifter. Materials and Methods Forty male weight-lifters were recruited and divided into 4 groups (n=10 each) and as the following groups: control (C), fasting (F), training (T) and fasting-training (F-T). The T an...

diabetes (impaired fasting glucose, impaired glucose tolerance) and even those with high-normal glucose levels [3] . Numerous studies have demonstrated greater insulin resistance (i.e., lower insulin sensitivity) in certain demographic groups: older subjects vs. younger subjects; African Americans vs. Caucasians; sedentary persons vs. active persons, among other examples. However, these differe...

BACKGROUND Diabetes mellitus, impaired fasting glucose level, or insulin resistance are associated with increased risk of cardiovascular disease. OBJECTIVES To determine the efficacy of gemfibrozil in subjects with varying levels of glucose tolerance or hyperinsulinemia and to examine the association between diabetes status and glucose and insulin levels and risk of cardiovascular outcomes. ...

Insulin-mediated glycogen synthase activity in skeletal muscle correlates with the rate of insulin-mediated glycogen deposition and is reduced in human subjects with insulin resistance. To assess the role of glycogen synthase phosphatase as a possible mediator of reduced glycogen synthase activity, we studied 30 Southwestern American Indians with a broad range of insulin action in vivo. Percuta...

INTRODUCTION In this study, we examined the effects of the alpha-glucosidase inhibitors acarbose and voglibose on postprandial plasma glucose and serum triglyceride levels in patients with type 2 diabetes mellitus. METHODS Twenty-one Japanese patients with type 2 diabetes were enrolled in this study. Subjects had been treated with voglibose for at least 3 months. They underwent a 400 kcal bal...

BACKGROUND Depression and bipolar illness are associated with a 2-3 fold increase in the prevalence of diabetes. However, it is unknown whether variation in mood affects glucose metabolism. The aim of this study was to assess whether changes in affect were related to fasting plasma glucose and glycated haemoglobin. METHODS 379 men and 441 women who took part in the 2003 Health Survey for Engl...

BACKGROUND About 9% of average dietary energy intake in the United States comes from fructose. Such a high consumption raises concern about the metabolic effects of this sugar. OBJECTIVE The objective of this study was to determine the effect of dietary fructose on plasma lipids. DESIGN The study was conducted in the General Clinical Research Center at Fairview-University of Minnesota Medic...