Zolpidem is a non-benzodiazepine drug that has selectivity for the gamma-aminobutyric acid (GABA) receptors. We experienced paradoxical effect of zolpidem in a 48-year-old male patient with hypoxic-ischemic brain injury after cardiac arrest. The patient was in stupor and could not communicate. His Glasgow Coma Scale (GCS) was E2M4V2 and Rancho Los Amigos (RLA) was grade III to IV. Zolpidem was ...

Developing methods to detect deviations from usual medical care may be useful in the development of automated clinical alerting systems to alert clinicians to treatment choices that warrant additional consideration. We developed a method for identifying deviations in medication administration in the intensive care unit that is based on learning logistic regression models from past patient data ...

OBJECTIVE To test the vulnerabilities of a wide range of computerized physician order entry (CPOE) systems to different types of medication errors, and develop a more comprehensive qualitative understanding of how their design could be improved. MATERIALS AND METHODS The authors reviewed a random sample of 63,040 medication error reports from the US Pharmacopeia (USP) MEDMARX reporting system...

Introduction Medication errors represent a serious issue affecting the U.S. health care system, accounting for the largest category of patient safety incidents within the larger category of medical errors. One report estimated that at least 1.5 million preventable medication errors occur in the U.S. each year. A list of high-alert medications (those with the highest potential for patient harm i...

Current techniques employed in security alert correlation area for multi-step attack recognition purpose are intricate to be performed due to the complexity of the methods and huge computing workload generated during alert analysis and processing. In this paper, we proposed a new method of alert correlation aiming at providing concentrated security event information and thus finding multi-step ...

PURPOSE Consensus recommendations to help ensure safe insulin use in hospitalized patients are presented. SUMMARY Insulin products are frequently involved in medication errors in hospitals, and insulin is classified as a high-alert medication when used in inpatient settings. In an initiative to promote safer insulin use, the American Society of Health-System Pharmacists (ASHP) Research and Ed...

Purpose: Muscle activation of the proximal parts is necessary for distal activities. In fact, proximal muscles provide stabilized and controlled base for distal parts activities. The purpose of this systematic review was to determine whether hand grip task can alert the activation of shoulder girdle muscles. Methods: A literature search was done in PubMed, Scopus, Elsevier, Ovid, CINAHL, S...

Intrusion alert correlation is multi-step processes that receives alerts from heterogeneous log resources as input and produce a high-level description of the malicious activity on the network. The objective of this study is to analyse the current alert correlation technique and identify the significant criteria in each technique that can improve the Intrusion Detection System (IDS) problem suc...

BACKGROUND The accountable care organization (ACO), one of the most promising and talked about new models of care, focuses on improving communication and care transitions by tying potential shared savings to specific clinical and financial benchmarks. An important factor in meeting these benchmarks is an ACO's ability to manage medications in an environment where medical and pharmacy care has b...