BACKGROUND The kidney is the most damaged organ in asphyxiated full-term infants. The severity of its damage is correlated with the severity of neurological damage. We determined the prevalence of perinatal asphyxia-associated acute kidney injury (AKI). METHODS We conducted a prospective cohort study including 60 full-term neonates admitted at the Kenyatta National Hospital newborn unit (NBU)...

We examined neuromuscular activity during stochastic (variable intensity) 100-km cycling time trials (TT) and the effect of dietary carbohydrate manipulation. Seven endurance-trained cyclists performed two 100-km TT that included five 1-km and four 4-km high-intensity epochs (HIE) during which power output, electromyogram (EMG), and muscle glycogen data were analyzed. The mean power output of t...

Discussion • The proposed architecture and data flow are designed to transform raw HIE data into trustworthy data and improve data integrity by examining data quality attributes of physiological compatibility, completeness, and redundancy. • By filtering out previously processed data and retaining only new HIE data, the architecture eliminates duplicate processing of discrete data from incoming...

Urinary S100A1B and S100BB were measured to detect cases at risk of hypoxic-ischemic encephalopathy (HIE) in asphyxiated newborns. We recruited 42 asphyxiated infants and 63 healthy term neonates. S100A1B and S100BB were measured at first urination (time 0) and at 4 (time 1), 8 (time 2), 12 (time 3), 16 (time 4), 20 (time 5), 24 (time 6), 72 (time 7) hours after birth. 20 infants had no/mild HI...

OBJECTIVE To determine the clinical utility of serum neutrophil gelatinase-associated lipocalin (NGAL) as an early marker of acute kidney injury in asphyxiated neonates with hypoxic ischemic encephalopathy (HIE). DESIGN Cohort study. SETTINGS National Intensive Care Unit of Maternity Hospital, Ain Shams University, Cairo, Egypt. PATIENTS The study included 30 term asphyxiated neonates (8 ...

In this paper, the author examines the critical issues that have emerged in the area of electronic healthcare information exchange (HIE) in the United States. An interpretive, longitudinal study was conducted over a total of four years through a study of seven field cases. This paper aggregates findings from these seven efforts into one research study for a more comprehensive view of HIE issues...

Perinatal hypoxic-ischemic encephalopathy (HIE) is an important cause of brain injury in the newborn and can result in long-term devastating consequences. Perinatal hypoxia is a vital cause of long-term neurologic complications varying from mild behavioural deficits to severe seizure, mental retardation, and/or cerebral palsy in the newborn. In the mammalian developing brain, ongoing research i...

The growing use of health information technology has also led to an increase in the adoption and use of electronic health information exchange (HIE). While large hospitals and healthcare systems have been at the forefront of implementing HIE, little is known about the state of adoption by small clinics, a large but little researched group. Using the institutional perspective we propose examinat...