A main target in the treatment of hypertension is the angiotensin-converting enzyme (ACE). This enzyme is responsible for producing angiotensin II, a potent vasoconstrictor. Therefore, one of the targets in the treatment of hypertension is to inhibit ACE activity. Hence, this study's aim is to use computational studies to demonstrate that the proposed heterocyclic compounds have a molecular aff...

Grapes are significant sources of nutritional antioxidants as well as biologically active dietary components. This study was carried out to determine the amount of total phenols, anthocyanins and antioxidant activity of 35 grapevine (Vitis vinifera L.) cultivars grown in Fars province (Iran). Ripened bunches were randomly harvested from grapevine collection in Zarghan (Fars province, Iran) Agri...

the genus verbascum l. belongs to the family scrophulariaceae and includes plants that have been used widely in traditional medicine for a long time. methanolic extracts of three verbascum species from flora of iran were in vitro screened for their possible antioxidant activities by three complementary test systems, namely dpph free radical-scavenging, metal chelating activity and β-carotene/li...

The deficiency of robust and practical methods for 18F-radiofluorination is a bottleneck for positron emission tomography (PET) tracer development. Here, we report the first transition-metal-assisted 18F-deoxyfluorination of phenols. The transformation benefits from readily available phenols as starting materials, tolerance of moisture and ambient atmosphere, large substrate scope, and translat...

An operationally simple ipso fluorination of phenols with a new deoxyfluorination reagent is presented.

Insects from a variety of Orders have been shown to detoxify phenols by conjugation with glucose and this mechanism has been suggested as a systematic biochemical characteristic of insects (Smith, 1955a). The phenols may be foreign compounds or may be those formed in the normal course of metabolism (Smith, 1955b, 1964; Kent & Brunet, 1959; Stay & Roth, 1962; Butenandt, Biekert, Kubler & Linzen,...

Phenols exert a great influence on the dynamic process of Cd in the soil-plant interface. We investigated the influence of phenols on the biogeochemical behavior of cadmium in the rhizosphere of Avicennia marina (Forsk) Vierh. All combinations of four levels of cadmium (0, 1, 2 and 4 mg/kg DW) and two levels of phenol (0 and 15 mg/kg DW) were included in the experimental design. We found that p...

Photosynthesis inhibition data were determined with thylakoids o f the green alga Chlamy­ domonas reinhardtii on twenty-two 2-bromo-4-nitro-6-alkyland 2,4-dinitro-6-alkyl-phenols. Wild type and five different mutants o f the algae were employed with defined changes in the psbA gene and a single amino acid substitution in the herbicide binding protein D 1 o f photo­ system II. Their response to ...

BACKGROUND N-acetyltransferases (NAT) 1 and 2 are polymorphic enzymes catalyzing the metabolic activation of heterocyclic amines. We investigated the modifying effects of NAT1 and NAT2 polymorphisms on the association of meat consumption, heterocyclic amine intake, and smoking with colorectal cancer risk. METHOD In the Multiethnic Cohort study, participants completed a smoking history and a f...