hepatomegaly (Nievel, 1969). The animals were killed 18h after the last dose of phenobarbitone. The rate of protein synthesis was assessed in uivo in dual-labelled experiments with [3H]and [14C]-leucine as precursors. Liver subcellular fractions were obtained by zonal and isopycnic ultracentrifugation. Various plasma and liver proteins, fibrinogen and plasminogen were fractionated and purified ...

BACKGROUND Frequent blood transfusion in patients with beta thalassemia major can lead to iron overload especially in liver. Chronic iron overload could cause cirrhosis of the liver. Transfusion- transmitted hepatitis B and C also could develop cirrhosis in individuals. MATERIALS AND METHODS The present cross- sectional descriptive study is to assess hepatomegaly and liver enzymes in 100 pati...

fanconi- bickel syndrome (fbs) is a rare type of glycogen storage disease (gsd) characterized by hepatomegaly, proximal renal tubular acidosis (rta) and marked growth retardation. we report a case of fbs presenting with diabetic ketoacidosis and transient neonatal diabetes. a female infant, product of consanguineous marriage presented with diabetic ketoacidosis at age 33 days, and was treated a...

recognition of typhoid hepatitis is important since it has to be differentiated from other common ailments in our country such as viral, malarial or amoebic hepatitis. early institution of specific therapy in cases of typhoid hepatitis carries a good prognosis. in our study, 107 patients with positive blood or bone marrow cultures for salmonella typhi, were evaluated for hepatomegaly and abnorm...

The present work is a prospective, observational, hospital based study on 100 sero positive cases of dengue infection, admitted to Dhaka Children Hospital, Dhaka, Bangladesh during the period 2000 -2001. The patients were in the age group 8 months to 14 years with a mean age of 8.3 years. The serological tests were performed by rapid strip test. Primary dengue infection (only Ig M positive) was...

Transient myeloproliferative disorder (TMD), restricted to newborns with trisomy 21, is a megakaryocytic leukemia that although lethal in some is distinguished by its spontaneous resolution. Later development of acute myeloid leukemia (AML) occurs in some. Prospective enrollment (n = 135) elucidated the natural history in Down syndrome (DS) patients diagnosed with TMD via the use of uniform mon...

The progression and variation of pathology during infections can be due to components from both host or pathogen, and/or the interaction between them. The influence of host genetic variation on disease pathology during infections with trypanosomes has been well studied in recent years, but the role of parasite genetic variation has not been extensively studied. We have shown that there is paras...

One hundred and one patients (51 females and 50 males), presenting with unexplained hepatomegaly were investigated. The histological findings on liver biopsy included normal architecture (36), changes of viral hepatitis (5), round cell infiltration in portal tract (10), fatty changes (14), hepatic malignancy (8), biliary disease (3), infections of the liver (12), cirrhosis of liver (6) and a mi...

Hepatic involvement of amyloidosis is common. Diffuse infiltration with hepatomegaly is a usual radiologic finding of hepatic amyloidosis. To our knowledge, this is the first case of amyloidosis involving the liver that presented as a mass.

Neuroblastoma (NBL) is a neuroectodermal tumor derived from neural crest cells. The biological and clinical behavior of NB is extremely heterogenous. We here report a newborn who presented as 4S NBL with a massive hepatomegaly resulting in IVC syndrome.