Treatment based on traditional medicine is very popular in developing world due to inexpensive properties. Nowadays, several types of preparations based on medicinal plants at different dose have been extensively recognized in the diseases prevention and treatment. In this vista, latest findings support the effect of Curcuma longa and its chief constituents curcumin in a broad range of diseases...

The hepato protective effect of the methanolic extract of Pongamia Pinnata flowers, an indigenous. Ayurvedic medicinal plant in India, was studied in rats with lead acetate induced hepatotoxicity. Administering 160 mg/kg b.wt/day of lead acetate for 90 days to male albino rats resulted in significantly elevated levels of ALT, AST, GGT, ALP, Bilirubin and protein were also observed on lead aceta...

Hepatitis viruses (HAV, HBV, HCV, HDV and HEV) are attributed to a wide spectrum of acute and chronic liver diseases, including carcinomas. Worldwide, >250 million become chronically infected by HBV and ~150 million by HCV every year. Though, new hepatotropic viruses, such as HGV, GBV, TTV and SENV are identified in chronic liver diseases, thousands still suffer of unknown etiology. Despite a p...

In the present study, ethanolic extract of ginger on lead acetate induced toxicity was studied in male wistar albino rats. Seven groups of rats were used in the study. Glutathione peroxidase, Glutathione reductase, Glutathione-S-transferase, Catalase and Superoxide dismutase were decreased in lead acetate treated (200mg/kg body weight, once daily for eight weeks) group. However treatment with e...

This study tested the hypothesis that chronic ethanol-induced injury in rats may be modified by the hydrophobicity of the bile acid pool. The supplementation to chronic ethanol feeding (28 days) with chenodeoxycholate, a hydrophobic bile salt, aggravated steatosis (accumulation of triacylglycerols and cholesterol esters), lipoperoxidation and cytolysis (expressed as elevations of activities of ...

This study sought to investigate the ameliorating effects of soy 11S protein on the impacts of alcohol consumption in rat hepatocytes and in reducing total cholesterol levels and total lipid levels in the serum. Liver histology and the clinically important enzyme markers (Aspartate Aminotransferase: AST and Alanine Aminotransferase: ALT) of rats, administered with both alcohol and soy 11S prote...

The flavonoid silymarin and one its structural components, silibinin, have been well characterized as hepato-protective substances. However, little is known about the biochemical mechanisms of action of these substances. This review deals with recent investigations to elucidate the molecular action of the flavonoid. Three levels of action have been proposed for silymarin in experimental animals...