Ebola hemorrhagic fever (EHF) was first reported in 1976 with two concurrent outbreaks of acute viral hemorrhagic fever centered in Yambuku (near the Ebola river), Democratic Republic of Congo, and in Nzara, Sudan. The current outbreak of the Ebola virus was started by reporting the first case in March 2014 in the forest regions of southeastern Guinea. Due to infection rates raising over 13,000...

Crimean-Congo hemorrhagic fever is a common disease between humans and animals that transmitted to through infected ticks, contact with animals, humans. In this paper, we present boxed model for the transmission of virus. With help fixed-point theory, our proposed system investigated in detail prove its unique solution. Given Caputo fractional-order derivative preserves system’s historical memo...

Crimean-Congo hemorrhagic fever virus (CCHFV) causes severe human disease. The CCHFV medium RNA encodes a polyprotein which is proteolytically processed to yield the glycoprotein precursors PreGn and PreGc, followed by structural glycoproteins Gn and Gc. Subtilisin kexin isozyme-1/site-1 protease (SKI-1/S1P) plays a central role in Gn processing. Here we show that CCHFV-infected cells deficient...

in Mexico (6) and the United States (7). In the United States, several pregnant women died, and the hospitalization rate for pregnant women was 4× higher than for the general population (8). Despite a fairly high birth rate on Reunion Island (19 births/1,000 population), our small series does not support these fi ndings. During the epidemic (July 20– September 20, 2009), acute respiratory infec...

conclusions the present study showed that cchf is highly prevalent in high risk occupational groups in zahedan, iran. further surveillance, teaching and prevention programs are recommended. results out of 362 patients with cchf (86% male, 14% female; with age range 12-78 years), 123 (34%) were slaughterhouse workers, 103 (28.5%) livestock handlers and farmers, 32 (9%) housewives, 7 (2%) student...

Crimean Congo hemorrhagic fever virus (CCHFV) is one of the most severe viral zoonozes. It is prevalent throughout Africa, Asia and southern Europe. Limited availability of sequence data has hindered phylogeographic studies. The complete genomic sequence of all three segments of 14 Crimean Congo hemorrhagic fever virus strains isolated from 1958-2000 in Russia, Central Asia and Africa was ident...

African monkey species are natural hosts of simian hemorrhagic fever virus (SHFV) and develop persistent, asymptomatic infections. SHFV was previously shown to also cause a rapid onset fatal hemorrhagic fever disease in macaques. Infection of macaques with a new isolate of SHFV from persistently infected baboon sera, that showed high nucleotide identity with the lab strain LVR, resulted in vire...

Dengue fever, dengue hemorrhagic fever and dengue shock syndrome are the prevalent mosquito borne viral infections worldwide. The dengue virus belongs to the genus flavivirus with conserved RNA domains peptidase_S7 and dexHc among its members. The secondary structures for RNA domains peptidase_S7 and DexHc are hence predicted and discussed with other known viral RNA structures to glean structur...

Background and Aims: Crimean-Congo hemorrhagic fever (CCHF) is a fatal viral disease that occurs in approximately 30 countries. It has the most extensive geographic range among the tick-borne viruses that affect human health. CCHF viruses have a tripartite RNA genome consisting of large (L), medium (M) and small (S) segments. This study was undertaken to determine the genetic relationship of CC...

Sequential titration of infective virus and complement-fixing antigen in brain and liver of suckling mice infected with the following virus strains-Dugbe (a new arbovirus), Congo (related to Crimean hemorrhagic fever virus), yellow fever, dengue 1 and dengue 2-showed a progressive increase in titer after infection. High titers of both infective virus and complement-fixing antigen were demonstra...