Hemoglobin in solution augments the rate of steady state diffusion of oxygen. The flux of oxygen exceeds the diffusive flux by an amount, the facilitated flux, which is constant for a given hemoglobin concentration and is invariant with changing oxygen tension. The facilitated flux is inversely proportional to the length of the diffusion path. Facilitation decreases with increasing molecular si...

background & aim: marshmallow (althaea officinalis) is one of the most popular medicinal plants used in traditional medicine with antibacterial and antioxidant properties. this study was conducted to evaluate the effects of marshmallow extract (althaea officinalis l.) administration on blood cells and biochemical parameters of carp liver. experimental: 150 carp (weighing 37.65 ± 4.40 g) wer...

BACKGROUND Many factors affect the accuracy of hemoglobin concentration values. In this study, we evaluated whether the hemoglobin concentration obtained by means of arterial blood gas (ABG) co-oximetry and complete blood count (CBC) central laboratory techniques clinically correlate when using simultaneous measurements of hemoglobin concentration obtained during complex spine fusion surgery. ...

BACKGROUND Anemia refers to a condition having low hemoglobin concentration. Anemia is considered a major risk factor for unfavorable pregnancy outcomes. This is the first study describing the pattern of hemoglobin concentration during pregnancy and its relationship to areas of high and low altitudes in Balochistan (the largest of Pakistan's four provinces). The main objective of this study was...

OBJECTIVE To determine the response, in terms of fecal hemoglobin excretion and clinical symptoms, of normal 9 1/2-month-old infants to being fed cow milk. DESIGN Longitudinal (before-after) trial in which each infant was fed formula for 1 month (baseline) followed by 3 months during which cow milk was fed. SETTING Healthy infants living in Iowa City, Iowa, a town with a population of about...

In hemoglobin Richmond (beta102 leads to Lys), amino acid substitution has occurred at the same site as the mutation in hemoglobin Kansas (beta102 Asn leads to Thr), a variant with very low oxygen affinity. Although hemoglobin Richmond has been shown to have increased tetramer-dimer dissociation, its oxygen affinity has been inferred to be normal from studies on hemolysates of carriers. We have...

Stoichiometric titrations of human hemoglobin with carbon monoxide show that the interaction of hemoglobin with ligand is accompanied by proportional changes in both the Soret and visible absorption bands. This linearity has been observed in neutral solutions, both in the presence and absence of 2 M NaCl, and in alkaline solutions at pH 9.2. It is concluded that the liganded intermediates takin...

Background: Blood is a specialized connective tissue with complete and unchangeable identity. Although almost 400 blood grouping antigens have been reported, the ABO and Rh is recognized as the major clinically significant blood group antigens which are also known to vary from one population to another. This study therefore sought to study the frequency of these indices and hemoglobin concentra...

INTRODUCTION The critical care management of traumatic brain injury focuses on preventing secondary ischemic injury. Cerebral oxygen delivery is dependent upon the cerebral perfusion pressure and the oxygen content of blood, which is principally determined by hemoglobin. Despite its importance to the cerebral oxygen delivery, the precise hemoglobin concentration to provide adequate oxygen deliv...

Ten patients with sickle cell anemia underwent partial exchange transfusion with hemoglobin-A-containing cells using a technique that allowed hemoglobin concentration and blood volume to remain constant. The mean fraction of hemoglobin-A in these patients increased from 9% to 55%, but the mean hemoglobin concentration increased by only 1.44 g/dl. The exchange resulted in a large improvement in ...