Background: Chronic hemodialysis (HD) in the 1960s encompassed a wide variety of prescriptions from twice weekly to five times per week HD. Over time, HD prescriptions in the West became standardized at three times per week, 2.5–4 h per session, with occasional additional treatments for volume overload. Summary: When clinical trials of dialysis dose failed to show significant benefit of extendi...

BACKGROUND Frequent hemodialysis (HD) may be associated with an increased risk of vascular access complications. Studies addressing vascular access outcomes in frequent HD show conflicting results. METHODS We searched Medline for trials looking at vascular access outcomes in frequent HD. RESULTS Nineteen studies met the inclusion criteria; only studies with a control group were included for...

Peritoneal dialysis (PD) and conventionalin-center hemodialysis (HD) are treatment options for patients with end-stage kidney disease (ESKD). However, their impacts on all-cause mortality in ESKD have not been determined.

Objective: Cystatin C is considered an important marker for the detection of renal dysfunction. It was aimed to determine cystatin levels, status oxidant-antioxidant and inflammation in hemodialysis (HD) patients. Methods: The study groups consisted 20 HD patients healthy controls. Blood samples were obtained from control group before hemodialysis. Serum C, total antioxidant capacity (TAC), oxi...

PURPOSE The lifespan of maintenance hemodialysis patients is reduced mainly because of cardiovascular complications due to accelerated atherosclerosis and impaired angiogenesis. We aimed to compare the effect of unfractionated heparin (UFH) and enoxaparin used as anticoagulants during hemodialysis (HD) on circulating levels of heparin-binding, anti-angiogenic Endostatin, pro-inflammatory RANTES...

Background: Hepatitis B (HB) vaccination is a recommended procedure in all dialysis patients, but its efficacy has not been perfect. In the current study, we aimed to conduct a comprehensive review of the literature to find and pool data of the randomized trials evaluating the impact of serum albumin levels on the immunogenicity of HB vaccination in dialysis patients. Methods: Literature searc...

OBJECTIVE Pulmonary hypertension (PH) has been described in hemodialysis (HD) patients and has been associated with increased morbidity and mortality. Our objective was to determine the prevalence of pulmonary hypertension in patients on regular hemodialysis. METHODS This cross sectional study was conducted in Department of Nephrology, Liaquat National Hospital Karachi from April 2013 to Marc...

Abstract Background A novel hemodialysis (HD) system employing electrolyzed water containing molecular hydrogen (E-HD) has been developed to improve the bio-compatibility of HD. This study examined impact E-HD on changes in redox state during HD and HD-related fatigue. Method single-arm, prospective observational 63 patients chronic (41 males; mean age, 72 ± 9 years; median duration HD, 7 years...

OBJECTIVE To determine patient and dialysis services-related factors associated with seroconversion of hepatitis C virus (HCV) in hemodialysis (HD) patients. STUDY DESIGN Cross-sectional study. PLACE AND DURATION OF Department Nephrology, Mayo Hospital, King Edward Medical University (KEMU), Lahore, from January to December, 2018. METHODOLOGY All patients on regular HD for more than three month...

Hemodialysis (HD) is the main treatment modality for patients with end-stage kidney disease. Cardiovascular diseases (CVD) are highly prevalent in HD and leading cause of death this population, mortality from CVD approximately 20 times higher than that general population. Traditional non-traditional cardiovascular risk factors accelerate progression exacerbate prognosis patients. This review pr...