INTRODUCTION Sinusitis is a common morbidity in general population, however little is known about its occurrence in severely immunocompromised patients undergoing allogeneic hematopoietic stem cell transplantation. OBJECTIVE The aim of the study was to analyze the literature concerning sinusitis in patients undergoing allogeneic bone marrow transplantation. METHODS An electronic database se...

Background: There is a worldwide effort to present novel approaches for the development of tolerance-induction treatments in regenerative medicine, after years of investigation in clinical transplantation. Particularly, novel approaches are based on controlling the immune response, including the application of biomaterials or imitation of antigen-specific peripheral tolerance in either solid-or...

introduction: human hematopoietic stem cells (hhscs) have been used for transplantation in hematologic failures. because the number of hhscs per cord blood unit is limited, the expansion of these cells is important for clinical application. it has been reported that cytokines and feeder layer provide a perspective to in vitro expansion of hhscs. in this regard, cord blood cd34+ cells expanded a...

Allogeneic hematopoietic stem cells transplantation is one of the effective methods treating patients with diseases blood system. Establishment complete (100%) donor chimerism among main indicators successful in such cases. Monitoring makes it possible both to assess graft acceptance, and also potentially predict risk developing primary/secondary failure, relapse, graft-versus-host disease. The...

Introduction . Infections are among the most common complications after allogeneic hematopoietic stem cell transplantation. Aim — to provide a literature review on main characteristics of infectious allogenic transplantation and risk factors for their development. Main findings Apart from direct such as neutropenia, hypogammaglobulinemia, lymphopenia, there indirect transplant-related condition...