نتایج جستجو برای: hematopoietic cells morphology

تعداد نتایج: 1526130  

2001
Maryalice Stetler-Stevenson Diane C. Arthur Nicholas Jabbour Xiu Y. Xie Jeff Molldrem A. John Barrett David Venzon

The myelodysplastic syndromes (MDSs) are characterized by bilineage or trilineage dysplasia. Although diagnostic criteria are well established for MDS, a significant number of patients have blood and bone marrow findings that make diagnosis and classification difficult. Flow cytometric immunophenotyping is an accurate and highly sensitive method for detection of quantitative and qualitative abn...

2001
Maryalice Stetler-Stevenson Diane C. Arthur Nicholas Jabbour Xiu Y. Xie Jeff Molldrem A. John Barrett David Venzon Margaret E. Rick

The myelodysplastic syndromes (MDSs) are characterized by bilineage or trilineage dysplasia. Although diagnostic criteria are well established for MDS, a significant number of patients have blood and bone marrow findings that make diagnosis and classification difficult. Flow cytometric immunophenotyping is an accurate and highly sensitive method for detection of quantitative and qualitative abn...

آبرون, سعید, ابراهیمی, مرضیه, اقدمی, ناصر, بهاروند, حسین, گنجی, فاطمه,

Background: Human embryonic stem cells (hESCs) are capable of self-renewal and large-scale expansion. They also have the capacity to differentiate into a variety of cell types including liver, cardiac and neuron cells. However, it is not yet clear whether hESCs can differentiate to hemangioblasts under in-vitro conditions. Hemangioblasts are bipotential progenitors that can generate hematopoiet...

Journal: :cell journal 0

introduction: umbilical cord blood is a rich source of hematopoietic cells and can be used in the clinical setting for hematopoietic cell transplantation in graft versus host disease (gvhd). a number of different drugs have been used as prophylaxis against gvhd including corticosteroids, cyclosporine a (cy a) and fk506. in this study, the in vitro effects of fk506 on cord blood mononuclear cell...

Journal: :The Tohoku journal of experimental medicine 2010
Kibom Kim Norio Suzuki Kinuko Ohneda Naoko Minegishi Masayuki Yamamoto

Eosinophils contribute to the pathophysiology of allergic and infectious diseases, albeit their molecular functions remain unknown. Mature eosinophils are identified by their unique morphology and staining characteristics. However, it is difficult to fractionate living eosinophils by flow cytometry because these granulocytes express multiple cell surface markers that are shared by other cells o...

In the recent decade, liver diseases with high mortality rate have became one of the major health problems worldwide. Liver transplantation is the most effective and the standard treatment for decompensated liver disease, but, shortage of available organs and inaccuracy in modeling of the liver diseases are the most limiting issues in treatment. Regenerative medicine and cell based therapy str...

Journal: :Thrombosis and haemostasis 2004
Nelli Baal Kerstin Reisinger Henning Jahr Rainer M Bohle Olin Liang Karsten Münstedt C V Rao Klaus T Preissner Marek T Zygmunt

A significant number of hematopoietic stem/progenitor cells (HSPC) in human umbilical cord blood could serve as a reservoir for the placental vasculature, yet, their morphological and functional features are not completely understood. Here, we describe the characterization of purified CD133(+) progenitor cells from umbilical cord blood, a subset of CD34(+) hematopoietic progenitors that were gr...

Journal: : 2022

The article has summarized the available data about regulatory T cells, describing in-detail stages of their studying, development, classification, mechanisms immunosuppression in general terms and also context allogeneic hematopoietic stem cells transplantation. effect immunosuppressive agents on this cell population is considered. role pathogenesis both acute chronic graft-versus-host disease...

Journal: :Acta biomaterialia 2013
Maude L Cuchiara Kelsey L Horter Omar A Banda Jennifer L West

Hematopoietic stem cells (HSCs) are currently utilized in the treatment of blood diseases, but widespread application of HSC therapeutics has been hindered by the limited availability of HSCs. With a better understanding of the HSC microenvironment and the ability to precisely recapitulate its components, we may be able to gain control of HSC behavior. In this work we developed a novel, biomime...

Journal: :Blood 2015
Andreas Reinisch Nathalie Etchart Daniel Thomas Nicole A Hofmann Margareta Fruehwirth Subarna Sinha Charles K Chan Kshemendra Senarath-Yapa Eun-Young Seo Taylor Wearda Udo F Hartwig Christine Beham-Schmid Slave Trajanoski Qiong Lin Wolfgang Wagner Christian Dullin Frauke Alves Michael Andreeff Irving L Weissman Michael T Longaker Katharina Schallmoser Ravindra Majeti Dirk Strunk

In the last decade there has been a rapid expansion in clinical trials using mesenchymal stromal cells (MSCs) from a variety of tissues. However, despite similarities in morphology, immunophenotype, and differentiation behavior in vitro, MSCs sourced from distinct tissues do not necessarily have equivalent biological properties. We performed a genome-wide methylation, transcription, and in vivo...

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