Abstract Background Treatments are often unavailable for rare disease patients, especially in low-and-middle-income countries. Reasons this include lack of financial support therapies and onerous regulatory requirements approval drugs. Other barriers reimbursement, administrative infrastructure, knowledge about diagnosis drug treatment options. The International Rare Diseases Research Consortiu...

BACKGROUND AND OBJECTIVES Staphylococcus aureus bacteremia (SAB) continues to be a major problem related to both community and nosocomially acquired infection. Nevertheless few data are presently available in literature about this infection in patients with hematologic malignancies. DESIGN AND METHODS The purpose of this retrospective study was to report further data on the clinical character...

BACKGROUND The nationwide statistical analysis of hematologic malignancies in Korea has not been reported yet. METHODS The Korea Central Cancer Registry and the Korean Society of Hematology jointly investigated domestic incidence rates and prevalence of hematologic malignancies occurred between 1999 and 2008, and analyzed survival rates of patients who were diagnosed between 1993 and 2008. Da...

By LAWRENCE BERMAN, M.D., ALFRED A. KLEIN, M.D., HERMAN J. LINN, M.D. AND GAYLORD S. BATES, M.D. I N DISEASES affecting the reticulo-endothelial system, involvement of the spleen may result in serious hematologic disturbances requiring immediate treatment. Reports of secondary, or symptomatic hypersplenism with isolated or combined cytopenias of the peripheral blood include diagnoses of hepatic...

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health convened a Working Group on the Microbiome in Cardiovascular, Pulmonary and Hematologic Health and Diseases from June 25, 2014, to June 26, 2014. The Working Group's central goal was to define what major microbiome research areas warranted additional study in the context of heart, lung, and blood (HLB) di...

STUDY OBJECTIVES Surgical subxiphoid drainage of the pericardial cavity has been established as a safe and effective method of treatment of pericardial effusion; however, the risk factors affecting survival of these patients have not been clarified. The aim of this study was to investigate the risk factors affecting the short-term and long-term survival of patients with pericardial effusion sub...

Education and End of Life in Chronic Kidney Disease: Disparities in Black and White Daniel Cukor* and Paul L. Kimmel *Department of Psychiatry and Behavioral Sciences, Downstate Medical Center, State University of New York, Brooklyn, New York; and Division of Kidney Urologic and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health...