نتایج جستجو برای: hematologic disease

تعداد نتایج: 1502143  

Journal: :Arquivos de neuro-psiquiatria 1965
H M Canelas N de Carvalho A G da Rocha

The treatment of subacute combined degeneration of the spinal cord (SCDSC) is based on a pretended etiological unity between the hematologic and neurologic manifestations, according to the old concept of the neuro-anemic syndrome. The first attempt of treatment of that disease was the liver therapy, introduced in 1926 by Minot and Murphy 2 3 , but the neurologic results did not correspond to th...

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Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2007
Jean-François Côté Sylvain Kirzin Andrew Kramar Jean-François Mosnier Marie-Danièle Diebold Isabelle Soubeyran Anne-Sophie Thirouard Janick Selves Pierre Laurent-Puig Marc Ychou

PURPOSE Irinotecan (CPT-11) is approved in metastatic colorectal cancer treatment and can cause severe toxicity. The main purpose of our study was to assess the role of different polymorphisms on the occurrence of hematologic toxicities and disease-free survival in high-risk stage III colon cancer patients receiving 5-fluorouracil (5FU) and CPT-11 adjuvant chemotherapy regimen in a prospective ...

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2017
Batool Alsheikh Madhuradhar Chegondi Balagangadhar Totapally

Objective To evaluate the threshold for platelet transfusion in children admitted to a pediatric intensive care unit (PICU). This is a retrospective chart review study, conducted at our tertiary level PICU and is related to critically ill pediatric patients who required platelet transfusion. Methods We retrieved the target patient population data from our blood bank database. The patients were ...

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Journal: :EJHaem 2023

Hematologic malignancy is a risk factor for severe coronavirus disease 2019 (COVID-19) in adults; however, data specific to children with leukemia are limited. High-quality infectious adverse event from the ongoing Children's Oncology Group (COG) standard-risk B acute lymphoblastic leukemia/lymphoma (ALL/LLy) trial, AALL1731, were analyzed provide disease-specific estimate of SARS-CoV-2 infecti...

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Journal: :Cancers 2021

Multiple myeloma (MM) is a hematologic cancer characterized by clonal proliferation of plasma cells in the bone marrow (BM). The progression, from early stages disease as monoclonal gammopathy undetermined significance (MGUS) and smoldering multiple (SMM) to MM occasionally extramedullary disease, drastically affected tumor microenvironment (TME). Soluble factors direct cell–cell interactions r...

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2011
Moon Ju Jang Hyeon Jin Park Sung-Soo Yoon Je-Hwan Lee Kyung-Duk Park Seok-Jin Kim Ho-Joon Im Jin-Seok Kim Jun-Ho Jang Suk-Joong Oh Hee-Soon Cho Jae-Woo Song Yeon-Jung Lim Ho-Young Kim

Korean National Health Insurance (NHI) was introduced in 1963 and became a nationwide health insurance after several law reforms in 1988. As a result of nationalization, coverage has expanded, and its service level has greatly improved since 1998 [1]. However, several diagnostic and therapeutic modalities for rare, incurable diseases such as malignant hematologic diseases are excluded from the ...

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2014
Worawut Choeyprasert Rungrote Natesirinilkul Pimlak Charoenkwan

Kasabach-Merritt phenomenon (KMP) is relatively rare in childhood and adolescents with high mortality rate because of its hemorrhagic complications and unresponsiveness to treatments such as corticosteroids, vincristine, intravascular embolization, and/or surgery. Propranolol, a β -adrenergic receptor blocker, has a promising efficacy against vascular tumors such as infantile hemangiomas. But l...

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Journal: :Blood 2007
Kazuyuki Matsuda Akira Shimada Nao Yoshida Atsushi Ogawa Akihiro Watanabe Shuhei Yajima Susumu Iizuka Kazutoshi Koike Fumio Yanai Keiichiro Kawasaki Masakatsu Yanagimachi Akira Kikuchi Yoshitoshi Ohtsuka Eiko Hidaka Kazuyoshi Yamauchi Miyuki Tanaka Ryu Yanagisawa Yozo Nakazawa Masaaki Shiohara Atsushi Manabe Seiji Kojima Kenichi Koike

Of 11 children with juvenile myelomonocytic leukemia (JMML) carrying RAS mutations (8 with NRAS mutations, 3 with KRAS2 mutations), 5 had a profound elevation in either or both the white blood cells and spleen size at diagnosis. Three patients had no or modest hepatosplenomegaly and mild leukocytosis at presentation but subsequently showed a marked increase in spleen size with or without hemato...

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2015
David Litwack

ASH represents more than 15,000 hematologists who are committed to the treatment of blood and blood-related diseases. These diseases include anemias (such as sickle cell disease and thalassemia), thrombosis and bleeding disorders, as well as malignant hematologic disorders such as leukemia, lymphoma, and myeloma. ASH members include clinicians who order Next Generation Sequencing (NGS) diagnost...

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Journal: :Blood 2018

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نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید

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    • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->