Cyclometallated compounds have been extensively studied, in particular those with palladium and platinum. This is because of their possible applications medicinal chemistry, as anticancer or antimicrobial agents; some cases, similar results cisplatin, carboplatin oxaliplatin. What also remarkable use homogeneous catalysts, for example, cross coupling reactions such Suzuki–Miyaura Mizoroki–Heck....

We report the synthesis of 1,4-dicarbonyl compounds and substituted alkenes (Mizoroki–Heck type coupling) starting from secondary tertiary alkyl halides vinyl acetate or styrene derivatives using visible-light photocatalysis.

PHILOSOPHY VII 1999 1. Opening WHAT IS THE EPISTEMOLOGICAL STATUS OF OUR KNOWledge of the truths of arithmetic? Are they analytic, the products of pure reason, as Leibniz held? Or are they high-level empirical truths that we know only a posteriori, as some empiricists, particularly Mill, have held? Or was Kant right to say that, although our knowledge that ‘5+7=12’ depends essentially upon intu...

Pd-catalyzed oxidative Heck reactions of coumarins were developed via simultaneous C-H functionalization at the C3 position of coumarins under aerobic conditions.

A facile ligand-free palladium-catalyzed intramolecular Heck reaction of β-hydrogen-containing secondary benzylic bromides was developed, which affords pyrroline derivatives with good regioselectivities.

A mild heterogeneous, ligand-free protocol for Sonogashira and Heck couplings has been developed and used to access several biologically important deoxynucleoside derivatives in a facile manner.