BACKGROUND Asthma is a chronic inflammatory disease characterized by airways hyper-responsiveness (AHR), reversible airway obstruction, and airway inflammation and remodeling. We previously showed that Syk modulates methacholine-induced airways contractility in naïve mice and in mice with allergic airways inflammation. We hypothesize that Syk plays a role in the pathogenesis of AHR; this was ev...

House dust mite (HDM) protease allergens, through cleavages of critical surface proteins, drastically influence the initiation of the Th2 type immune responses. However, few human protein substrates for HDM proteases have been identified so far, mainly by applying time-consuming target-specific individual studies. Therefore, the identification of substrate repertoires for HDM proteases would re...

125 The Association betweenMast Cells andRemodelling of the Small Airways in Chronic Asthma Kenneth Snibson, PhD, and Joanne Van der Velden,. Veterinary Science, University of Melbourne, Parkville, Australia. Background: Repeated airway challenges with House Dust Mite (HDM) allergen results in marked remodelling and mast cell hyperplasia in the small airways of allergic sheep. We now examine ma...

125 The Association betweenMast Cells andRemodelling of the Small Airways in Chronic Asthma Kenneth Snibson, PhD, and Joanne Van der Velden,. Veterinary Science, University of Melbourne, Parkville, Australia. Background: Repeated airway challenges with House Dust Mite (HDM) allergen results in marked remodelling and mast cell hyperplasia in the small airways of allergic sheep. We now examine ma...

An analysis of the model underpinning the description of the spread of HIV infection of CD4(+)T cells is examined in detail in this work. Investigations of the disease free and endemic equilibrium are done using the method of Jacobian matrix. An iteration technique, namely, the homotopy decomposition method (HDM), is implemented to give an approximate solution of nonlinear ordinary differential...

Hybrid Dynamical Models (HDM) can describe all phenomena arising in hybrid technical systems. In this brief contribution we deene a hybrid reachability set to examine the reachability of HDM. Additionally, the stability of hybrid equilibrium points and their domains of attraction is considered. R esum e: Dans cette communication, nous pr esentons une nouvelle approche de mod elisation des syst ...

Accurate estimation of small-scale forest biomass is a prerequisite and basis for trading carbon sinks optimizing the allocation forestry resources. This study aims to develop plot-scale methodology estimating aboveground (AGB) that combines horizontal distribution model (HDM) sampling techniques improve efficiency, reduce costs provide reliability biomass. Simao pine (Pinus kesiya var. langbia...

Higher levels of IgE-containing immune complexes (IC) have been reported in sera from patients with allergic diseases than in sera from controls. To evaluate the possibility of an IC-mediated mechanism in the pathogenesis of bronchial asthma, we measured circulating C3-containing IgE IC (C3-IgE IC) using anti-C3 ELISA from 20 house dust mite (HDM)-sensitive asthmatics, 20 non-atopic asthmatics,...