Spatial data partitioning (SDP) plays a powerful role in distributed storage and parallel computing for spatial data. However, due to skew distribution of spatial data and varying volume of spatial vector objects, it leads to a significant challenge to ensure both optimal performance of spatial operation and data balance in the cluster. To tackle this problem, we proposed a spatial coding-based...

Hadoop is now the de facto standard for storing and processing big data, not only for unstructured data but also for some structured data. As a result, providing SQL analysis functionality to the big data resided in HDFS becomes more and more important. Hive is a pioneer system that support SQL-like analysis to the data in HDFS. However, the performance of Hive is not satisfactory for many appl...

The rapid development of remote sensing (RS) technology has resulted in the proliferation of high-resolution images. There are challenges involved in not only storing large volumes of RS images but also in rapidly retrieving the images for ocean disaster analysis such as for storm surges and typhoon warnings. In this paper, we present an efficient retrieval of massive ocean RS images via a Clou...

We compared the DNA-binding activity of transcription factors and gene expression patterns in BJ human diploid fibroblasts (HDFs) expressing or not telomerase (hTERT) in stress-induced premature senescence (SIPS). Senescent BJ cells were also studied. Hydrogen peroxide (H2O2)-induced SIPS modulated gene expression in both BJ and hTERT-BJ1 cells. Increased p21(WAF-1) mRNA level was amongst the c...

Hadoop is one of open source software technology that is used for processing large amount of data across clusters of commodity servers in distributed manner. Mainly it is designed to provide high fault tolerance and scale up a single server to thousands numbers of machines. Hadoop uses Hadoop distributed file system (HDFS) which is open source implementation of Google File System (GFS) for data...

The aim of the present study was to determine if human amnion‑derived mesenchymal stem cells (HAMSCs) exert a protective effect on ultraviolet A (UVA) irradiation-induced human dermal fibroblast (HDF) senescence. A senescence model was constructed as follows: HDFs (104‑106 cells/well) were cultured in a six‑well plate in vitro and then exposed to UVA irradiation at 9 J/cm2 for 30 min. Following...

Cloud computing services are becoming more and more popular. However, the high concentration of data and services on the clouds make them attractive targets for various security attacks, including DoS, data theft, and privacy attacks. Additionally, cloud providers may fail to comply with service level agreement in terms of performance, availability, and security guarantees. Moreover, users may ...

The platelet-derived growth factor beta receptor (PDGFbetaR) plays an important role in proliferation and motility of fibroblasts. We have been investigating the effects of sustained PDGFbetaR activation in mortal human diploid fibroblasts (HDFs), which are typically difficult to transform. We have previously shown that the bovine papillomavirus E5 protein, through its ability to crosslink and ...

Glioblastoma multiforme (GBM) is the most common and most aggressive malignant brain tumor. Despite optimal treatment and evolving standard of care, the median survival of patients diagnosed with GBM is only 12-15 months. In this study, we combined progesterone (PROG) and temozolomide (TMZ), a standard chemotherapeutic agent for human GBM, to test whether PROG enhances the antitumor effects of ...

Due to brisk growth of data volume in many organizations, large-scale data processing became a demanding topic for industry as well as for academic fields. Hadoop is widely adopted in Cloud Computing environment for unstructured data. Hadoop is an open source, a java based distributed computing framework, and supports large-scale distributed data processing. In the recent years, Hadoop Distribu...