The evolution of microstructure and mechanical properties of almost fully amorphous Mg(72) Zn(23) Ca(5) and crystalline Mg(70) Zn(23) Ca(5) Pd(2) alloys during immersion in Hank's balanced salt solution (HBSS), as well as their cytocompatibility, are investigated in order to assess the feasibility of both materials as biodegradable implants. Though the crystalline Mg(70) Zn(23) Ca(5) Pd(2) samp...

In recent years, thanks to the advancement of robotics and mechatronics, new and more effective devices for the restoration and replacement of sensory-motor function in disabled people have been developed. In all these systems, user acceptability is strictly connected to several issues such as the residual abilities of the subject, the mechatronic characteristics of the robot, and also the inte...

BACKGROUND The high childhood mortality and life-long complications associated with sickle cell anemia (SCA) in developing countries could be significantly reduced with effective prophylaxis and education if SCA is diagnosed early in life. However, conventional laboratory methods used for diagnosing SCA remain prohibitively expensive and impractical in this setting. This study describes the cli...

We present an analysis of 991 heartbeat stars (HBSs) from the OGLE Collection Variable Stars (OCVS). The sample consists 512 objects located toward Galactic bulge (GB), 439 in Large Magellanic Cloud (LMC) and 40 Small (SMC). model $I$-band light curves using analytical flux variations, reflecting tidal deformations between stars. distributions parameters that include eccentricity, orbital incli...

Abstract Background Fetal hemoglobin (HbF) levels play significant role in lowering down the morbidity and mortality sickle cell disease (SCD) patients. Coinheritance of heme oxygenase-1 (HMOX1) rs2071746:A > T polymorphism may contribute to variable HbF Indian SCD Aim Objective This study was aimed evaluate HMOX1 its impact on level Materials Methods One-hundred twenty confirmed cases 50 he...

Abbreviations: AM, acetoxymethylester; BSA, bovine serum albumin; DMEM, Dulbecco’s modified Eagle medium; FITC, fluorescein isothiocyanate; GM-CSF, granulocyte-macrophage colony-stimulating factor; HBSS, Hanks’ balanced salt solution; ICAM-1, intercellular adhesion molecule-1; LSC, laser scanning cytomety; NF-κB, nuclear factor-kappa B; PBS, phosphate buffered saline; PI, propidium iodide; PLP,...

The glycocalyx is an important anti-inflammatory and anti-adhesive barrier at the luminal side of endothelial cells. Glycocalyx volume was significantly reduced in sickle cell patients (HbSS/HbSbeta(0)-thalassemia median 0.47L, IQR 0.27-0.66, HbSC/HbSbeta(+)-thalassemia 0.23L, 0.0-0.58) compared with controls (1 x 10(9)L, 0.52-1.77) (p=0.03). Reduced glycocalyx may be a new factor in the pathop...

Background: As to whether the presence of Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency ameliorates or worsens sickle cell disease (SCD) is still not clear. Aim and Objectives: This study was therefore aimed at investigating whether the presence of G6PD deficiency among SCD subjects (HbSS and HbSC) would have any significant impact on the severity of crisis and haematological indices. Sub...

BACKGROUND: Sickle cell disease is a common genetic disorder in Nigeria. OBJECTIVES: To determine the steady state haematocrit, liver size and spleen size in children with sickle cell disease and the factors that influence them. METHODS:This was a retrospective study of children with sickle cell disorders who attended the anaemia clinic of the Children’s Outpatient Department, University Colleg...

OBJECTIVE Green tea extract (GTE) was shown to be effective in preserving periodontal ligament fibroblasts (PDLFs) of avulsed teeth. This study aimed at determining the potential of GTE in preserving the viability of PDLFs comparing with different storage media. MATERIALS AND METHODS Periodontal ligament cells were obtained from freshly extracted healthy impacted third molars and cultured in ...