This article assesses two Harmonic Balance Method-based numerical Lagrangian strategies for the characterization of periodic response a mechanical system subject to unilateral contact constraints. The model used evaluation is an academic rod facing obstacle that firstly considered as equivalent stiffness (flexible) and then rigid obstacle. Nonlinear frequency curves are obtained through arc-len...

background: according of high prevalence of internet addiction and its numerous consequences among university students and based on importance of theory based educational intervention implementation on prevention and decreasing behavioral disorders such as internet addiction, current study performed to determine the effect of blended educational intervention based on health belief model on inte...

OBJECTIVE Although seat belt use can significantly decrease the risk of injury, few car drivers make use of seat belts in Iran. The aim of this study was to test the utility and efficiencyof the theory of planned behavior (TPB) and the health beliefmodel (HBM) in predicting intention to use a seat belt among car drivers in Sabzevar, Iran. METHODS A cross-sectional, correlational design was em...

OBJECTIVES The application of stem cells holds great promises in cell transplants. Considering the lack of optimal in vitro model for hepatogenic differentiation, this study was designed to examine the effects of laminin matrix on the improvement of in vitro differentiation of human bone marrow mesenchymal stem cells (hBM-MSC) into the more functional hepatocyte-like cells. MATERIALS AND METH...

objective: diabetes mellitus is one of the most common medical problems worldwide. approximately 18% of persons over 65 years old are diabetic. who estimates that the prevalence rate of diabetes (4% in 1995) will increase to 5.6% in 2025. diabetic foot problems are potentially the most preventable long–term complication for diabetes. the purpose of this study was to test the utility of the heal...

Although Lrp5 is known to be an important contributor to the mechanisms regulating bone mass, its precise role remains unclear. The aim of this study was to establish whether mutations in Lrp5 are associated with differences in the growth and/or apoptosis of osteoblast-like cells and their proliferative response to mechanical strain in vitro. Primary osteoblast-like cells were derived from cort...

The use of earplugs in loud music venues is confined to a small minority who wish to avoid hearing damage from excessive noise exposure. Using the framework of the health belief model (HBM), structured interviews were held with 20 earplug-wearing clubbers. Qualitative analysis revealed the HBM constructs relevant to understanding this group's motivation to protect their hearing. Personal experi...

Ways of accelerating recovery of the mucous membrane immune system in lethally irradiated mice following syngeneic bone marrow transplantation were studied over a 35-day period by quantification of jejunal intraepithelial lymphocytes (lEis) and lamina propria plasma cells. Recovery after a low bone marrow dose allowing 1 00% animal survival (IBM) was compared with a high (five times minimal) do...

PURPOSE: Mesenchymal Stromal Cells (MSCs) are a promising source for cell therapy due to their proregenerative and immunomodulatory effects. These properties can be enhanced by engineering MSCs to overexpress and secrete growth factors favorable to wound healing processes. Here, we aimed to develop a platform for targeted gene insertion in human bone marrow (hBM)-MSCs that utilizes CRISPR/Cas9 ...

A comment by Buhaug et al. attributes disagreement between our recent analyses and their review articles to biased decisions in our meta-analysis and a difference of opinion regarding statistical approaches. The claim is false. Buhaug et al.’s alteration of our metaanalysis misrepresents findings in the literature, makes statistical errors, misclassifies multiple studies, makes coding errors, a...