نتایج جستجو برای: haplotyping

تعداد نتایج: 559  

Journal: :Comparative and Functional Genomics 2002
Mostafa Ronaghi Elahe Elahi

Comparative genomics, analyzing variation among individual genomes, is an area of intense investigation. DNA sequencing is usually employed to look for polymorphisms and mutations. Pyrosequencing, a real-time DNA sequencing method, is emerging as a popular platform for comparative genomics. Here we review the use of this technology for mutation scanning, polymorphism discovery and chemical hapl...

2015
Kaomud Tyagi Vikas Kumar Devkant Singha Rajasree Chakraborty

South East Asia pest thrips species, Thrips parvispinus (Karny), is a serious pest on a number of agricultural and horticultural crops in a number of plant families. Based on an integrated approach of morphology and DNA barcoding, invasion of this serious pest is reported first time from India on papaya plantations. Molecular data have corroborated with the morphological identification. Haploty...

Journal: :Human molecular genetics 2007
Mark A Jobling Iek Chi C Lo Daniel J Turner Georgina R Bowden Andrew C Lee Yali Xue Denise Carvalho-Silva Matthew E Hurles Susan M Adams Yuet Meng Chang Thirsa Kraaijenbrink Jürgen Henke Ginevra Guanti Brian McKeown Roland A H van Oorschot R John Mitchell Peter de Knijff Chris Tyler-Smith Emma J Parkin

Structural polymorphism is increasingly recognized as a major form of human genome variation, and is particularly prevalent on the Y chromosome. Assay of the Amelogenin Y gene (AMELY) on Yp is widely used in DNA-based sex testing, and sometimes reveals males who have interstitial deletions. In a collection of 45 deletion males from 12 populations, we used a combination of sequence-tagged site m...

2003
Dan Gusfield

The next high-priority phase of human genomics will involve the development of a full Haplotype Map of the human genome. It will be used in large-scale screens of populations to associate specific haplotypes with specific complex genetic-influenced diseases. A key, perhaps bottleneck, problem is to computationally determine haplotype pairs from genotype data. An approach to this problem based o...

Journal: :Theor. Comput. Sci. 2005
Vineet Bafna Sorin Istrail Giuseppe Lancia Romeo Rizzi

SNP haplotyping problems have been the subject of extensive research in the last few years, and are one of the hottest areas of Computational Biology today. In this paper we report on our work of the last two years, whose preliminary results were presented at the European Symposium on Algorithms (Proceedings of the Annual European Symposium on Algorithms (ESA), Vol. 2161. Lecture Notes in Compu...

2008
Michael Elberfeld Till Tantau

Haplotyping, also known as haplotype phase prediction, is the problem of predicting likely haplotypes based on genotype data. This problem, which has strong practical applications, can be approached using both statistical as well as combinatorial methods. While the most direct combinatorial approach, maximum parsimony, leads to NP-complete problems, the perfect phylogeny model proposed by Gusfi...

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