Children with Down's syndrome have developmental delays, particularly regarding cognitive and motor development. Fine motor skill problems are related to motor development. They have impact on occupational performances in school-age children with Down's syndrome because they relate to participation in school activities, such as grasping, writing, and carrying out self-care duties. This study ai...

Abstract The ability to use and manipulate the hands is essential for completing daily activities such as dressing, food preparation, medication adherence, but declines with age. Assessments of hand function typically include measures maximum strength despite our recent findings that fine force control may be more indicative than strength. purpose this study was determine effectiveness a hand-b...

HYPOTHESIS Objective assessment of surgical skill has recently been shown to be possible through the use of dexterity-based and video analysis systems. The aim of this study was to synchronize these 2 modalities to produce a comprehensive surgical assessment tool. DESIGN The Imperial College Surgical Assessment Device is a dexterity-based motion analysis device that has been developed in the ...

25 Temporary deafferentation of the upper limb, with ischemic or anesthetic nerve block, has 26 rapid effects on sensorimotor cortex. Cutaneous anesthesia of the forearm has recently been 27 found to improve sensory and motor function of the paretic hand in chronic stroke patients. 28 However, the neurophysiological mechanisms are unknown. The aim of this study was to 29 investigate the behavio...

Exercise, such as cardiovascular fitness training, has been shown to have utility in improving executive function but is difficult for older adults with low mobility to perform. Accordingly, there is interest in the development of regimens other than high mobility exercises for older adults with low mobility. The aim of the present study was to evaluate the association between sensory motor fun...

BACKGROUND Although cell therapy is a promising approach after cerebral cortex lesion, few studies assess quantitatively its behavioral gain in nonhuman primates. Furthermore, implantations of fetal grafts of exogenous stem cells are limited by safety and ethical issues. OBJECTIVE To test in nonhuman primates the transplantation of autologous adult neural progenitor cortical cells with assess...

OBJECTIVES Functional neuroimaging and voxel-based morphometry studies have confirmed the important role of the cerebellum in motor behavior. However, little is known about the relationship between cerebellar gray (GMv) and white matter (WMv) volume and manual motor performance in aging individuals. This study aims to quantify the relationship between cerebellar tissue volume and manual motor p...

The objective of this study was to investigate the effect of dexterity on the magnitude of signal changes in functional magnetic resonance imaging (fMRI) in the cervical spinal cord with unilateral finger-tapping. Right-handed healthy volunteers were investigated with blood oxygenation level-dependent (BOLD) fMRI. Spinal cord BOLD functional MR images were acquired from 10 healthy right-handed ...