We studied the kinetic properties of high- and low-molecular-mass forms of alkaline phosphatase purified from serum and bile, to clarify their interrelationships. They were found to share virtually identical kinetic properties, and to obey the same general kinetics as the liver-derived isoenzyme from serum and the low-molecular-mass isoenzyme from bile with regard to optimum conditions of assay...

Natto is a traditional Japanese food made from soybeans fermented by strains of Bacillus subtilis natto. It gives off a strong ammonia smell during secondary fermentation, and the biochemical basis for this ammonia production was investigated in this study. When natto was fermented by strain r22, ammonia production was shown to involve degradation of soybean proteins releasing amino acids, and ...

A series of dual inhibitors containing a 1,5-diarylpyrazole and a urea were designed, synthesized, and evaluated as novel COX-2/sEH dual inhibitors in vitro using recombinant enzyme assays and in vivo using a lipopolysaccharide (LPS) induced model of pain in rats. The best inhibition potencies and selectivity for sEH and COX-2 over COX-1 were obtained with compounds (21b, 21i, and 21j) in which...

Physiological energetics of cobia Rachycentron canadum were quantified for 18 to 82 days posthatch (dph) hatchery-reared juveniles to better understand energy transformation and its implications in growth and survival. Mean oxygen consumption rates (MO2 ; mg O2 h ) of fish fed ad libitum and fish that were starved significantly increased with increasing wet mass (M; g), MO2 1⁄4 1 4291M 8119 and...

Pulverized cornified epithelium of human skin was divided into a "soluble fraction" and a "residue." About half of the "soluble fraction" proved to be soluble epidermal keratin (keratin A); the remainder, dialyzable substances of low molecular weight. The "residue" contained epidermal keratin and resistant cell membranes of cornified cells. Epidermal keratin was found to form an oriented and de...

The asymmetric unit of the binuclear title compound, [Sn(2)(C(2)O(4))(C(6)H(5))(6)(CH(4)N(2)S)(2)], consists of one half of the organotin(IV) mol-ecule. The remainder is generated by a twofold rotation axis passing through the mid-point of the oxalate C-C bond. The Sn(IV) atom exhibits a distorted trigonal-bipyramidal coordination environment with the phenyl groups in equatorial positions and t...

urea is the most common form of nitrogen fertilizer used in sugar beet cultivation. urea has a high solubility and its losses are high and consequently its efficiency is low. it is supposed that urea solubility can be limited and its efficiency can be increased by using slow-release nitrogen fertilizers. by conducting an experiment in three important sugar beet cultivation areas of khorasan pro...

this experiment was conducted to improve the nutritive value of barley stubble for two consecutive years. after harvesting crop, at first year, a completely randomized design, with a 3 × 3 factorial experiment was conducted in which 27 plots were divided into nine treatments. the treatments including zero, 2.5 and five percent urea each with zero, three and six percent molasses were mixed with ...