Outer hair cells (OHCs) are innervated by type II afferent fibers of as yet unknown function. It is still a matter of debate whether OHCs perform exocytosis. If so, they would require presynaptic Ca2+ channels at their basal poles where the type II fibers make contacts. Here we show that L-type Ca2+ channel currents (charge carrier, 10 mM Ba2+) present in neonatal OHCs [postnatal day 1 (P1) to ...

background: hair dye poisoning, with main toxic component paraphenylene diamine, is a medical emergency. it is on increasing trend in developing countries due to wide availability and low cost of hair dyes. it carries a high mortality and does not have any specific antidote. case report:  twenty three years old patient presented with breathelessness along with difficulty in speaking for one hou...

osteoporosis, characterized by low bone mass and microarchitectural deterioration of bone tissue leading to enlarged bone fragility and a consequent increase in fracture risk is a leading cause of morbidity and mortality in elderly people. the mortality rate in elderly persons with hip fracture approaches 20%. half of them will be disabled in the remained life. iranian multicenter osteoporosis ...

background & aim:combretaceae family is   known for efficacy in the management of sickle cell disorder (scd). based on   the earlier reports of anti-sickling property of terminalia genus the study investigates in vitro antisickling properties of terminalia arjuna and terminalia   bellirica. experimental: anti-sickling   assay of methanolic and aqueous extract of t. arjuna and t. bellirica   on ...

Surface transportation networks are critical infrastructure that are frequently affected by volcanic ash fall. Disruption to surface transportation from volcanic ash is often complex with the severity of impacts influenced by a vast array of parameters including, among others, ash properties such as particle size and deposit thickness, meteorological conditions, pavement characteristics, and mi...

BACKGROUND One in four Swedish women suffers a hip fracture yielding high morbidity and mortality. We wanted to revalidate a 4-item clinical risk score and evaluate a portable heel bone mineral density (BMD) technique regarding hip and fragility fracture risk among elderly women. METHODS In a population-based prospective cohort study we used clinical risk factors from a baseline questionnaire...