Despite the recent rapid growth in genome-wide data, much of human variation remains entirely unexplained. A significant challenge in the pursuit of the genetic basis for variation in common human traits is the efficient, coordinated collection of genotype and phenotype data. We have developed a novel research framework that facilitates the parallel study of a wide assortment of traits within a...

OBJECTIVE To determine the most effective treatment parameters for laser-assisted hair removal using a Q-switched neodymium:yttrium-aluminum-garnet (Nd:YAG) laser. DESIGN Prospective study to determine the effectiveness of Q-switched ND:YAG laser-assisted hair removal under varying pretreatment protocols. Hair growth was assessed after laser treatment, and the results were compared with those...

this research was conducted to study morphological and evaluation of genetic diversity of 15 grape cultivars in collections of agriculture and natural resources, research center of khorasan razavi based on completely randomized design with four replications. results showed extensive range of variations among cultivars and measured traits. in some key traits of tests for distinctness uniformity ...

in order to investigation of morphological traits, yield and its components in three cultivars of grain sorghum (kimia, sepideh, payam) and two promising lines (m5, m2) under four density (240000, 205000, 170000 and 135000 plant/m2), experiment was conducted as factorial design based on randomized complete block design with three replications in birjand agricultural research station, during 200...

Stereocilia, finger-like projections forming the hair bundle on the apical surface of sensory hair cells in the cochlea, are responsible for mechanosensation and ultimately the perception of sound. The actin cytoskeleton of the stereocilia contains hundreds of tightly cross-linked parallel actin filaments in a paracrystalline array and it is vital for their function. Although several genes have...

Insects and arachnids are often quite hairy. The reasons for this high density of sensory hairs are unknown. Previous studies have predicted strong hydrodynamic coupling between densely packed airflow-sensitive hairs. Flow perturbation owing to single hairs and between tandem hairs, however, has never been experimentally measured. This paper aims to quantify the extent of flow perturbation by s...

After noise- or drug-induced hair-cell loss, the sensory epithelia of the avian inner ear can regenerate new hair cells. Few molecular markers are available for the supporting-cell precursors of the hair cells that regenerate, and little is known about the signaling mechanisms underlying this regenerative response. Hybridoma methodology was used to obtain a monoclonal antibody (mAb) that stains...

We conducted a functional analysis of seed dispersal and its plasticity in response to density in Arabidopsis thaliana by growing morphologically diverse ecotypes under high and low density and measuring seed dispersion patterns under controlled conditions. Maternal plant architectural traits such as height and branching, and fruit traits such as dehiscence and silique length influenced various...

Hair follicle growth cycle proceeds through a series of stages in which strict control of cell proliferation, differentiation, and cell death occurs. Transgenic mice expressing human papillomavirus type 16 E6/E7 papillomavirus oncogenes in the outer root sheath (ORS) display a fur phenotype characterized by lower hair density and the ability to regenerate hair much faster than wild-type mice. R...

this experiment was conducted, to study the effect of planting time and planting density on savory (satureja sahendica bornm.) in 2012 in alborz research station, research institute of forests and rangelands, karaj, iran. the experiment was carried out in split plot in time in the form of a randomized complete block design with three replicates. the main plots were planting times in two levels ...