The course of a VHS (viral haemorrhagic septicaemia) infection in brown trout Salmo trutta fario L. in a stream was followed for 4 yr using anti-VHS virus antibodies a s the indication of infection. Trout were caught by electrofishing and the presence of anti-VHS virus antibody in the serum was determined by counter-current immunoelectrophoresis. There were fluctuations in the prevalence of ant...

In general, viral haemorrhagic septicaemia virus (VHSV) isolates from marine fish species in European waters (genotypes GIb, GII and GIII) are non- to low virulent in rainbow trout. However, a VHSV isolation was made in 2007 from a disease outbreak in sea farmed rainbow trout in Norway. The isolate, named NO-2007-50-385, was demonstrated to belong to GIII. This isolate has attracted attention t...

Mammalian cytotoxic T cells as part of the adaptive immune system recognize virus-infected target cells by binding of their T-cell receptors (TCR) to classical MHC class I molecules loaded with viral peptides. Our previous studies have shown that the allele of the single dominant polymorphic classical MHC class I locus Onmy-UBA is identical in the rainbow trout clone C25 and in the permanent ra...