BACKGROUND Acquired haemophilia is an uncommon condition caused by the development of clotting factor inhibitors. To eliminate them, immunosuppressive therapy with corticosteroids and cytotoxic drugs is required. METHODS We describe a case of rituximab use in acquired haemophilia refractory to conventional therapy in a 63 year old male patient with chronic hepatitis C virus infection who was ...

The unintentional contamination of haemophilia patients with HIV in the early 1980s raised serious questions about the safety of blood product supplies worldwide. The events initiated a cascade of consequences for both infected patients and the national health systems of many countries, including the Islamic Republic of Iran. Lawsuits have been filed in the courts mostly in developed countries,...

1 Moore CP, Sarti DA, Louie JS. Ultrasonographic demonstration of popliteal cysts in rheumatoid arthritis. Arthritis Rheum 1975; 18: 577–80. 2 Fritschy D, Fasel J, Imbert JC, Bianchi S, Verdonk R, Wirth CJ. The popliteal cyst. Knee Surg Sports Traumatol Arthrosc 2006; 14: 623–8. 3 Rodrigue V, Shaughnessy WJ, Schmidt KA, Slaby JA, Gilchrist GS, Pruthi RK. Haemorrhage into a popliteal cyst: an un...

The fifth edition of the haemophilia B database lists in easily accessible form all known factor IX mutations due to small changes (base substitutions and short additions and/or deletions of < 30bp) identified in haemophilia B patients. The 1,142 patient entries are ordered by the nucleotide number of their mutation. Where known, details are given on: factor IX activity, factor IX antigen in ci...

The sixth edition of the haemophilia B database lists in easily accessible form all known factor IX mutations due to small changes (base substitutions and short additions and/or deletions of <30 bp) identified in haemophilia B patients. The 1380 patient entries are ordered by the nucleotide number of their mutation. Where known, details are given on factor IX activity, factor IX antigen in circ...

Intracranial hemorrhage in patients with hemophilia is associated high mortality and morbidity. We report a case of 15 years old boy haemophilia A, who presented spontaneous acute subdural hematoma underwent craniotomy for clot evacuation. The patient also received Factor VIII infusions peri-operatively along other measures, to decrease blood loss. signs raised intracranial pressure mannitol in...

13.00-14.30 Introduction to the meeting Global haemophilia care: what can be learned from emerging countries? Chairs: J. Astermark (SE), P. de Moerloose (CH) Low-dose replacement and prophylaxis in emerging countries A. Srivastava (IN) Cross-border care: heterogeneity of haemophilia care between countries and its consequences on patients’ management C. Hermans (CH) How can wealthy countries hel...

Haemophilia is a rare and congenital bleeding disorder caused by a genetic defect, resulting in a lack of or insufficient coagulation factors VIII or IX in the body. In affected individuals, this causes an inability to clot blood, leading to bleeds in the joints, muscles and soft tissues. If left untreated, this can lead to disability and sometimes death. It is widely agreed that the optimal st...

Haemophilia A is a bleeding disorder that has a spectrum of manifestations ranging from persistent bleeding after minor trauma to spontaneous haemorrhage. As an X-linked disease, it has a rare occurrence in females. We report a case of a pregnant patient with severe haemophilia A, who received epidural analgesia during labour. The prepartum, intrapartum and postpartum care of a patient with suc...