ABSTRACT The limitation of executive compensation has been a matter public and policy debate for at least 20 years. We examine regulatory action in Austria 2014 where the tax deductibility total value is unavoidably limited. find no average effects on growth or composition executives’ pay. However, limit affects managers firms with low bargaining power strong corporate governance, indicating th...

The pKa values of ionizable groups in proteins report the free energy of site-specific proton binding and provide a direct means of studying pH-dependent stability. We measured histidine pKa values (H3, H22, and H105) in the unfolded (U), intermediate (I), and sulfate-bound folded (F) states of RNase P protein, using an efficient and accurate nuclear magnetic resonance-monitored titration appro...

The high-affinity IgG receptor, FcgammaRI (CD64), is constitutively expressed exclusively on professional APCs. Human FcgammaRI binds monomeric IgG with high affinity and is, therefore, saturated in vivo. The binding of IgG to FcgammaRI causes receptor recycling, while Abs that cross-link FcgammaRI cause rapid down-modulation of surface FcgammaRI. Because studies performed in the absence of lig...

Oxidative stress is involved in the development and progression of disease. Because sodium aescinate has been reported to have immunity enhancing and antioxidative effects, we investigated its activity by employing a hepatocellular carcinoma (HCC) mouse model. Sixty BALB/c mice were randomly divided into four groups, including a 1.4 mg/kg treated group (n = 15), a 2.8 mg/kg treated group (n = 1...

Abstract Background Our previous studies demonstrated that the administration of crude Polysaccharide from Panax notoginseng (CPPN) can effectively prolong lifespan tumor-bearing mice via boosting host immune system as well weak cytotoxicity against hepatocellular carcinoma (HCC). In present study, Neutral (NPPN) were further purified polysaccharide isolated panax . The effects NPPN on function...