background and aims: influenza a viruses are important pathogens for humans especially in pandemic episodes. two adamantane derivates, amantadine and rimantadine, are used for prophylaxis and treatment of influenza a virus infections. however, single amino acid substitutions in the m2 transmembrane domain which lead to amantadine resistance of these viruses occur at residues 26, 27, 30, 31 or 3...

background influenza is a world-wide public health concern. it is one of the most important viral causes of acute respiratory illness, affecting all age groups, recurring several times during a lifetime. we assessed the antibody titers after vaccination against influenza among hiv-infected patients and health care workers (hcws). patients and methods during this before-after study, the antibody...

Influenza A virus (H1N1) 2009, a new swine-origin influenza A virus, has been spread worldwidely and caused great public fear. High-throughput transcriptomics and proteomics methods are now being used to identify H1N1 and H1N1-host interaction. This article reviews recent transcriptomics and proteomics research in H1N1 diagnosis, treatment, and H1N1 virus-host interaction, to offer some help fo...

BACKGROUND Healthcare workers have been identified as one of the high risk groups for being infected with influenza during influenza pandemic. Potential levels of absenteeism among healthcare workers in hospital settings are high. However, there was no study to explore the attitudes of healthcare workers in community setting towards the preparedness to the novel H1N1 influenza pandemic. The aim...

BACKGROUND We compared the clinical effectiveness of oseltamivir and zanamivir in children with influenza A (H1N1) virus, influenza A (H3N2) virus, and influenza B virus infections. METHODS Total febrile period and the duration of fever after the start of treatment were compared between an oseltamivir-treated group (mean age, 8.9 years; range, 4.0-15.9 years) and a zanamivir-treated group (me...

BACKGROUND Influenza virus is one of the major viral pathogens causing pediatric acute respiratory infection (ARI). The spread of pandemic influenza A (A(H1N1)pdm09) in 2009 around the globe had a huge impact on global health. OBJECTIVE To investigate the impact of A(H1N1)pdm09 on pediatric ARI in Vietnam. STUDY DESIGN An ongoing population-based prospective surveillance in central Vietnam ...

BACKGROUND Presentation of pandemic H1N1 influenza (H1N1) is widely evolving as it continues to involve different geographic locations and populations. This study was conducted to improve the precision of clinical diagnosis of H1N1 (2009) influenza infection in an outpatient setting. MATERIALS AND METHODS A prospective cross-sectional study was conducted among adult patients (age >15 years) w...

INTRODUCTION The cardiac manifestations of influenza A are broad, ranging from self-limited pericarditis to fatal cardiomyopathy. The 2009 H1N1 influenza A (H1N1) strain is a rare cause of pericarditis, and its role in developing a pericardial effusion leading to tamponade has infrequently been reported. CASE PRESENTATION We describe a case of a young female with no prior cardiovascular histo...

BACKGROUND To assess the knowledge, the attitudes, and the behaviour towards influenza A/H1N1 and the vaccination among health-care workers (HCWs). METHODS A sample of HCWs was selected from a random sample of non-teaching public hospitals, located in the cities of Naples and Avellino (Italy), received a self-administered anonymous questionnaire including questions about socio-demographic cha...

CDC first identified cases of respiratory infection with a novel influenza A (H1N1) virus in the United States on April 15 and 17, 2009. During seasonal influenza epidemics and previous pandemics, pregnant women have been at increased risk for complications related to influenza infection. In addition, maternal influenza virus infection and accompanying hyperthermia place fetuses at risk for com...