A cross-sectional survey was carried out on 2004-2005 in the Campania region, southern Italy, to study the multivariate geographical distribution of four different sheep helminths, i.e. Fasciola hepatica (liver fluke), Calicophoron (Paramphistomum) daubneyi (rumen fluke), Dicrocoelium dendriticum (lancet fluke), and the gastrointestinal strongyle Haemonchus contortus. A series of multivariate B...

Phytotherapy may be an alternative strategy for controlling gastrointestinal parasites. This study evaluated the anthelmintic efficacy of Eucalyptus citriodora essential oil (EcEO). The in vitro effects of EcEO were determined through testing the inhibition of egg hatching and larval development of Haemonchus contortus. EcEO was subjected to acute toxicity testing on mice, orally and intraperit...

Haemonchus contortus poses a severe hazard to the healthy development of sheep industry and threatens welfare sheep. Ivermectin is primary anthelmintic used for prevention treatment H. parasitism. However, widespread uncontrolled application ivermectin has resulted in spread resistant strains contortus. P-glycoprotein (P-gp) plays important roles pharmacology toxicology ivermectin, changes P-gp...

Abstract Themeda and Heteropogon are closely related grass genera frequently dominant in tropical C4 grasslands. Relationships between them poorly resolved, impeding ecological study, especially of T. triandra with a broad distribution from Africa to East Asia, H. contortus pantropical distribution. Our analyses plastome nuclear genomes comprehensive sampling demonstrate that neither genus is m...

The glutamate-gated chloride channels (GluCls) are members of the ligand-gated ion channel superfamily that are thought to be involved in the mode of action of ivermectin and mechanism of resistance. Using reverse-transcriptase PCR techniques, 2 full-length GluCl cDNAs, encoding GluClalpha3 and GluClbeta subunits, were cloned from Cooperia oncophora, a nematode parasite of cattle. The two seque...

Aim: To determine the effect of severity of Haemonchus contortus infection on performance and economics of raising kids fed on two respective plane of nutrition. Materials and Methods: The feeding trial was conducted for 120 days with non-descript female kids (3-5 months age). The kids were randomly allocated into two dietary treatments having normal protein normal energy (NPNE) and high protei...

Infection with the gastrointestinal nematode Haemonchus contortus causes considerable losses in the sheep industry. In this study, we evaluated the effect that climate has on third-stage larvae (L3) of H. contortus in terms of their migration from sheep feces to Brachiaria decumbens grass, as well as their distribution among the forage plants. Fecal samples containing H. contortus L3 was deposi...

AIM The aim of this study was to evaluate the potential possibility of crude larval and recombinant (rHcp26/23) antigens of Haemonchus contortus for immunization to control sheep hemonchosis. MATERIALS AND METHODS A total of 21 lambs were divided into five groups. Lambs were immunized with larval and recombinant (rHcp26/23) proteins at day 0 and day 14 and after that challenged with 5000 infe...

Blood sucking parasites elaborate mechanisms to counteract the hemostatic system of their victim. Haemonchus contortus worms use several mechanisms directed against the normal platelet hemostatic function. Platelet adhesion onto collagen and fibrinogen, and the ristocetin-mediated interaction of von Willebrand Factor with glycoprotein (GP) Ib were inhibited by the protein extract of adult worms...

The prevalence of concurrent nematode-trypanosome infections in traditionally reared West African Dwarf sheep and goats in eastern Nigeria was monitored over a 12-month period during 1987-1988. The most prevalent nematodes were Haemonchus contortus and Trichostrongylus colubriformis, which usually occurred together in all nematode infected animals. Their combined prevalence rates ranged from 90...