Traditionally, as a standard dose fractionation schedule, adjuvant radiotherapy for breast cancer has been performed using prescribed doses of 46–50 Gy divided into daily fractions 1.8–2 Gy. Overall, treatment took 5 weeks. In the 1990s, schedules higher (2.5–3 Gy), smaller number (hypofractionation), and reduced overall started in context clinical trials. First results revealed an equivalent c...