Prolonged residence of drug formulation in the nasal cavity is important for the enhancing intranasal drug delivery. The objective of the present study was to develop a mucoadhesive in-situ gelling nasal insert which would enable the reduced nasal mucociliary clearance in order to improve the bioavailability of metoclopramide hydrochloride. Metoclopramide hydrochloride is a potent antiemetic an...

Lesquerella fendleri seeds contain a cross-linked carbohydrate gum with viscoelastic properties that may be used for industrial and edible applications. Laboratory studies compared the rheological behavior of gum isolates obtained from whole seed, defatted hull, and defatted meal fractions. Gum yields and rheological properties were determined for gum isolates from each of these fractions. All ...

Xanthan gum is a biopolymer produced by Xanthomonas sp. XC6. In this study, xanthan gum is produced from potato starch using a stepwise bioprocess design. Potato starch is hydrolyzed using Bacillus sp. having amylase activity and 30.2 g/L reducing sugar was released, while Xanthomonas sp. XC6 can release only 14.5 g/L. Bacillus sp. hydrolyzed potato starch extract was further used as a carbon s...

the aim of this work was to optimize the coagulation-flocculation (cf) process applied tomunicipal wastewaters (ww). optimization of cf was performed to minimize chemical oxygen demand(cod), turbidity, sludge produced, and some metals in sludge. a box-behnken design was used to evaluate the effects and interactions of three factors such as type of biopolymer (guar, mesquite seed gum and opuntia...

the aim of this work was to optimize the coagulation-flocculation (cf) process applied tomunicipal wastewaters (ww). optimization of cf was performed to minimize chemical oxygen demand(cod), turbidity, sludge produced, and some metals in sludge. a box-behnken design was used to evaluate the effects and interactions of three factors such as type of biopolymer (guar, mesquite seed gum and opuntia...

in this paper, the effect of two domestic seeds hydrocolloids (basil seed and sage seed gums) and one commercial hydrocolloid (pectin) on characteristics of non-fat concentrated yoghurt was studied. for this purpose, effect of different concentrations of these gums (0.05, 0.1, 0.15 and 0.2%) on physicochemical and sensory properties after 1 and 7 days were investigated and compared with control...

PURPOSE This pilot study evaluated the acceptance and compliance of a xylitol chewing gum regimen by both children and classroom teachers in a Head Start program. METHODS Thirty-five children chewed 100% xylitol gum (XyliFresh 100%, Leaf, Inc., 500 Field Dr., Lake Forest, IL 60045 U.S.A.) three times a day over a three week period. Children's acceptance was evaluated using a picture selection...

Welan gum is a kind of novel microbial polysaccharide, which is widely produced during the process of microbial growth and metabolism in different external conditions. Welan gum can be used as the thickener, suspending agent, emulsifier, stabilizer, lubricant, film-forming agent and adhesive usage in agriculture. In recent years, finding optimal experimental conditions to maximize the productio...

materials and methods in a randomized clinical trial, 60 patients, scheduled for cesarean section were randomly divided in to 2 groups gum-chewing group (n = 30) and control group (n = 30) postoperatively. the patients in the gum-chewing group postoperatively chewed sugar free gum 3 times daily each time for 1 hour until discharge. the patients' demographic characteristics, duration of sur...

This study evaluated the effectiveness of nicotine chewing gum in smoking cessation, when incorporated into a behaviorally oriented self-help program. One hundred ninety-seven patients were randomly assigned to nicotine gum with a self-help manual, a self-help manual without gum, or a control condition, but received no further treatment from the prescribing physician. At six weeks, the nicotine...