Purpose-In order to assess major chromosomal abnormalities among sick neonate with dysmorphic feature and delayed milestones in Kolkata, a chromosome aberration survey was initiated in collaboration with Dr. B. C. Roy Post Graduate Institute for Pediatric Science ( Kolkata) is in progress. MethodsIn last two years, we have screened about 120 sick neonates (Indicated cases as per clinical findin...

South American Akodontini rodents are characterized by a large number of chromosome rearrangements. Among them, the genus Akodon has been extensively analyzed with classical and molecular cytogenetics, which allowed the identification of a large number of intra- and interspecific chromosomal variation due to Robertsonian rearrangements, pericentric inversions, and heterochromatin additions/dele...

Chromosomal abnormalities are one of the major causes of male infertility. But the exact mechanism by which chromosomal anomalies induces infertility is still not clear. Many studies have documented the chromosomal abnormalities ranging from 2.2% to 15.7% in infertile men. The present study has been carried out to document and find out the genetic cause of male infertility in the Southern regio...

Since the first description of human fragile sites (FS) more than 40 years ago, a variety of substances were reported to induce chromosomal breaks at non-random, breakage-prone regions. According to information available from human genome browsers aphidicolin, an inhibitor of DNA replication induces 77 of 88 known common FS. However, in the literature additional FS are reported, which are also,...

Rhagomys rufescens (Rodentia: Sigmodontinae) is an endemic species of the Atlantic forest from Southern and Southeastern Brazil. Some authors consider Rhagomys as part of the tribe Thomasomyini; but its phylogenetic relationships remain unclear. Chromosomal studies on eight specimens of Rhagomys rufescens revealed a diploid number of 2n = 36 and a number of autosome arms FN = 50. GTG, CBG and A...

BACKGROUND In this paper we describe work in progress in developing kernel methods for enzyme function prediction. Our focus is in developing so called structured output prediction methods, where the enzymatic reaction is the combinatorial target object for prediction. We compared two structured output prediction methods, the Hierarchical Max-Margin Markov algorithm (HM3) and the Maximum Margin...

While the genomes of many Mycoplasma species have been sequenced, there are no collated data on translational start codon usage, and the effects of alternate start codons on gene expression have not been studied. Analysis of the annotated genomes found that ATG was the most prevalent translational start codon among Mycoplasma spp. However in Mycoplasma gallisepticum a GTG start codon is commonl...

Turbulence is a major aviation hazard for both commercial and private aircraft. Currently, the clear-air turbulence forecasting tool Graphical Turbulence Guidance (GTG) is used by airline meteorologists and dispatchers for flight planning, and in part to determine operational Airman’s Meteorological Information (AIRMET) turbulence advisories; however, GTG has much higher resolution and intensit...

Keywords: chromosomal dermatoglyphics genetics infertility Polycystic ovarian syndrome PCOS Original Article Aims: To study and co-relate chromosomal abnormalities and dermatoglyphics in infertile female patients with PCOS. Method: 16 cases of PCOS and 16 normal females as controls were selected. Chromosomal study was done using whole blood culture method and GTG Banding in genetic laboratory. ...

Introduction One of the important causes of male infertility is aberration at the chromosomes. Aim The main purpose of this study was to determine the frequency and types of chromosomal aberration in infertile/sterile men whose samples were analyzed in the Center for Cytogenetics of Faculty of Medicine University of Sarajevo in the last four years. Methods A total of 353 infertile/sterile m...