rabson-mendenhall syndrome is a rare genetic disorder characterized by growth retardation, dysmorphisms, lack of subcutaneous fat, acanthosis nigricans, enlarged genitalia, hirsutism, dysplastic dentition, coarse facial features, paradoxical fasting hypoglycemia, postprandial hyperglycemia, extreme hyperinsulinemia and pineal hyperplasia. herein, we described a 10- year-old girl with physical f...

The 21st annual meeting of the Canadian College of Neuropsychopharmacology (CCNP) was marked by participation of an unprecedented number of registrants > 200, comprising psychiatrists, pharmacologists, and neuroscientists from Canada and the U.S.A. The presentations consisted of four plenary lectures, three award lectures, eight symposia, and 97 posters. The major themes in the meeting included...

BACKGROUND It is unclear whether associations between fetal growth and psychiatric and socioeconomic problems are consistent with causal mechanisms. AIMS To estimate the extent to which associations are a result of unmeasured confounding factors using a sibling-comparison approach. METHOD We predicted outcomes from continuously measured birth weight in a Swedish population cohort (n = 3 291...

We examined adrenergic regulation in patients with panic disorder by challenging 10 patients and 14 age-matched and sex-matched controls with intravenous infusions of clonidine hydrochloride (2 micrograms/kg), an alpha 2-adrenoreceptor agonist. Growth hormone, 3-methoxy-4-hydroxyphenylglycol (MHPG), blood pressure, heart rate, and behavioral (anxiety, sedation) responses were monitored. The dat...

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary disorder (estimated prevalence of 1 per 1000–1 2500 live births)1 characterized by development and growth multiple bilateral cysts eventually leading to end-stage renal replacement therapy.1

Stimulant-associated growth deficits in children with attention deficit hyperactivity disorder (ADHD) have long been a concern. Height deficits in preadolescence have been reported, but adult heights have been reported to be uncompromised. It is possible that the catch-up growth that occurs is related to ADHD-associated delayed maturation and not to the cessation of stimulant treatment. To date...

A simple model for an interface moving in a disordered medium is presented. The model exhibits a transition between the two universality classes of interface growth in the presence of quenched disorder. Using this model, it is shown that the application of constraints to the local slopes of the interface produces avalanches of growth that become relevant in the vicinity of the depinning transit...

Extensive Monte Carlo simulations are performed on a two-dimensional random field Ising model. The purpose of the present work is to study the disorder-induced changes in the properties of disordered spin systems. The time evolution of the domain growth, the order parameter, and the spin-spin correlation functions are studied in the nonequilibrium regime. The dynamical evolution of the order pa...

Starting from the general concept of behaviour disorder, in childhood, preschool and adolescence, this work descriptive boundaries all diagnostic hypotheses are defined, with an orientation for clinical, neurobiological therapeutic treatment, not leaving out socio-cultural, educational family contexts inherent to growth minor.

Initial suggestions that suppression of growth may be an intrinsic characteristic of attention-deficit/hyperactivity disorder (ADHD) have now largely been disproven. Although controversy persists regarding the possible negative effect of adrenergic stimulants on growth in children with ADHD, the consensus that appears to be reached in the scientific literature is that stimulant usage may cause ...