An asymmetric transfer hydrogenation of 2,3-disubstituted quinoxalines using a chiral frustrated Lewis pair of Piers' borane and (R)-tert-butylsulfinamide as the catalyst with ammonia borane as the hydrogen source has been successfully realized. For 2-alkyl-3-arylquinoxaline substrates, cis-tetrahydroquinoxalines were obtained as the predominant products in high yields with 77-86% ee. In contra...

Intertwined superfluid and density wave order in two dimensional He Ján Nyéki, Anastasia Phillis, Andrew Ho, Derek Lee, Piers Coleman, Jeevak Parpia, Brian Cowan, John Saunders Department of Physics, Royal Holloway University of London, Egham, Surrey, TW20 0EX, U.K. Department of Physics, Blackett Laboratory, Imperial College London, London SW7 2AZ, U.K. Center for Materials Theory, Department ...

In assessments of the seismic adequacy of existing steel bridges, the steel-to-concrete anchorage connections typically found at the base of steel truss piers can be potentially vulnerable, having little to no ductility and inadequate strength to resist seismic demands. Many other non-ductile failure locations may also exist along the seismic load path. Failure would result in unacceptable perf...

Background Pre-eclampsia is one of the leading causes of maternal death and morbidity in low-resourced countries due to delays in case identification and a shortage of health workers trained to manage the disorder. The objective of the PIERS on the Move (POM) project was to provide mid-level health workers with an evidence-based and low-cost decision aid to improve diagnosis and management of p...

The hydroboration of phosphaalkynes with Piers' borane (HB(C6 F5 )2 ) generated unusual phosphaalkenylboranes [RCH=PB(C6 F5 )2 ]2 that persisted as dimers in both solution and the solid state. These P2 B2 heterocycles underwent ring opening when subjected to nucleophiles, such as pyridine and tert-butylisocyanide, to yield monomeric phosphaalkenylborane adducts RCH=PB(C6 F5 )2 (L). DFT calculat...

Rene Aalbers, M.D.;* Bert Piers, M.D., P/i.D.;t Anton Eygelaar, M.D., Ph.D.A and Pieter E. Postmus, M.D., Ph.D.* A 62-year old woman was admitted to the emer gency unit because of a suddenly developing swelling of the neck. Three months earlier, hyperthyroidism had been diagnosed. At that time, a chest roentgenogram had been done (Fig 1). Except for changes in both apical parts of the lungs, pr...

Anna N. Seale, MBBChir, MRCP; Hideki Uemura, MD, MPhil, FRCS; Steven A. Webber, MBChB, MRCP; John Partridge, FRCR, FRCP, FRANZCR; Michael Roughton, MSc; Siew Y. Ho, PhD, FRCPath; Karen P. McCarthy, BSc; Sheila Jones, BSc; Lynda Shaughnessy, BN; Jan Sunnegardh, MD, PhD; Katarina Hanseus, MD, PhD; Hakan Berggren, MD, PhD; Sune Johansson, MD; Michael L. Rigby, MD, FRCP; Barry R. Keeton, MB, BS, FR...