BackgroundSodium-glucose cotransporter 2 inhibitors (SGLT2i) clinically reduce atherosclerosis and lower blood pressure. However, their impact on endothelial dysfunction in type diabetes (T2D) remains unclear. In this study, we investigated the protective effect underlying mechanism of SGLT2 inhibitor dapagliflozin diabetes.MethodsVascular reactivity was measured to assess vasoprotective a mous...

Air quality monitoring networks are challenging to implement due the bulkiness and high prices of standard instruments low accuracy most described low-cost approaches. This paper presents a low-cost, automated, self-powered analytical platform determine hourly levels O3 NO2 in urban atmospheres. Atmospheric air was sampled at constant airflow 100 mL min−1 directly into vials containing 800 µL i...

Nitrite (NO(2)(-)) is assumed to play an important role in regulation of vascular tone as a reservoir of nitric oxide (NO). To examine its physiological contribution, however, a sensitive method is required for determination of the true level of NO(2)(-) in biological samples. To this end, practical consideration to avoid NO(2)(-) contamination through the quantification procedure is important....

In $26+1$ space-time dimensions, we introduce a gravity theory whose massless spectrum can be acted upon by the Monster group when reduced to $25+1$ dimensions. This generalizes M-theory in many respects and name it Monstrous M-theory, or M$^{2}$-theory. Upon Kaluza-Klein reduction M$^{2}$-theory irreducibly splits as $\mathbf{1}\oplus\mathbf{196,883}$, where $\mathbf{1}$ is identified with dil...

Introduction: Mucositis has been a complication of great importance in antineoplastic treatments head and neck tumors because when not treated properly it can lead to the interruption radiotherapy or chemotherapy. Knowing that mucositis is common inflammatory condition patients undergoing nitric oxide (NO) be marker inflammation.
 Aim: seek an association between mucositis, pain NO levels ...

Chronic inflammation can lead to several diseases that represent the leading causes of mortality worldwide. Conventional treatment carry some risks. Therefore, research on herbal medicine are suspected having anti-inflammatory effects, such as Piper betle L., is important. This study aims investigate effect P. L. extract nitric oxide a pro-inflammatory mediator. The dried leaves were extracted ...

Stress and chronic pain have been shown to prevent the development of tolerance to morphine analgesia, which appears to be related to neuroendocrine activity and alternation in neurochemicals. Also the involvement of nitric oxide (NO) has been implicated in tolerance to morphine analgesia. In our pervious study, we showed that co-administration of swim stress (ss) with chronic morphine, prevent...

Various polymorphisms on endothelial nitric oxide synthase (eNOs) gene cause reduced production of NO, the endothelial relaxing factor, and may accelerate the process of atherosclerosis. The study designed to investigate the frequency of T-786C polymorphism of the eNOs gene in patients suffering from coronary artery disease (CAD) in north-west of Iran. One hundred twenty subjects including 60 p...

introduction: cigarette smoking affects nitric oxide production. the aim of this study was to determine associations between tobacco smoke and serum nitric oxide metabolites (nox) concentration. methods: serum nox concentration was measured by the griess method in 230 nonsmokers, 238 active, 196 passive and 29 waterpipe smokers. subjects were selected from participants of tehran lipid and gluco...

Photocatalytic coatings have potential as an air purifying technology for removal of pollutants such NOx gases, which are converted into and immobilized nitrate via photo-oxidation. This work is investigation the photocatalytic conversion nitrite in aqueous phase. The study this reaction important to understand mechanism through immobilization species nitrates takes place during conversion, esp...