Grape juices (V. vririferu) from vineyards at three locations in Israel were analyzed for carbon, hydrogen and nitrogen contents, metals, amino acids and glycerol, various stages of fermentation and post-fermentation. The contents varied with respect to the type of grape, area, year of collection and methods of vinification. The glycerol content of wine appears to be related to the duration of ...

Additional approaches to control malignancies are needed due to the emerging trends in the incidence of cancer of different organ sites. Due to the high frequency of hepatocellular carcinoma (HCC) and its poor prognosis, preventing HCC is an urgent priority. To explore the antioxidant and apoptotic pathways of grape seed extract (GSE) we induce HCC experimentally by diethylnitrosoamine (DEN) an...

SCOPE This work aims to evaluate changes in the fecal metabolomic profile due to grape seed extract (GSE) intake by untargeted and targeted analysis using high resolution mass spectrometry in conjunction with multivariate statistics. METHODS AND RESULTS An intervention study with six crossbred female pigs was performed. The pigs followed a standard diet for 3 days, then they were fed with a s...

The aim of the present study was to assess the anti-obesity effects of grape seed extract (GSE) supplement in C57BL/6J mice. Thirty mice were divided into three groups; normal diet control group (ND), high fat diet control group (HD) and high fat diet plus grape seed extract supplemented group (HD+GSE). Results were as follows: 1. GSE supplement reduced the weight gain in mice fed high fat diet...

this study has been done to survey of solvent system effect on extraction of grape seed extract and its antimicrobial properties. for this purpose, grape seed extracts were extracted with six different solvent systems. minimum bactericidal concentration (mbc) of extract on six spoilage and food-born pathogens was determined. the results indicated that mbc of different extracts have no significa...

Chen, Tzu Ying. Ph.D., Purdue University, December 2013. Brain Bioavailability of Polyphenols: Implications for Delivery of Brain Health Benefits. Major Professor: Elsa M. Janle and Mario G. Ferruzzi. Consumption of fruits and vegetables has been associated with neuroprotection and cognitive benefits throughout the life span. These associations have sparked interest in plant derived polyphenols...

Natural dietary antioxidants are studied for their ability to protect cells from miscellaneous damage. Grape seed extract (Vitis vinifera L., Vitacease) is a potent antioxidant. The present study aimed to investigate the protective effect of grape seed extract (GSE) against the possible testicular dysfunction caused by aluminium chloride (AlCl3) in male rats. Twenty sexually mature male albino ...

Introduction. Consumption of unripe grape juice (verjuice) has been portrayed by the traditional belief, as a means of combating dyslipidemia. We aimed to evaluate the effects of unripe grape juice consumption on lipid profile in healthy human volunteers. Methods. We asked 42 enrolled volunteers to drink 10 cc of verjuice within 30 minutes to 2 hours after lunch and 10 cc of it after dinner. Af...

AIMS In order to assess the potential for producing mycotoxins, fungi were isolated from wine producing grapes. METHODS AND RESULTS The isolates were identified and Penicillium expansum, the most well recognized mycotoxin producer, was analysed for mycotoxin production by TLC. Many of the strains produced patulin and/or citrinin, often depending on whether they were grown on a grape or yeast ...