نتایج جستجو برای: granulocyte colony stimulating factor g csf

تعداد نتایج: 1334693  

Journal: :Blood 1991
T R Ulich J del Castillo I K McNiece E S Yi C P Alzona S M Yin K M Zsebo

Recombinant rat stem cell factor (rrSCF) and recombinant human granulocyte colony-stimulating factor (G-CSF) coinjected for 1 week in rats cause a synergistic increase in mature marrow neutrophils accompanied by a striking decrease in erythroid and lymphoid marrow elements. The spleens of the same rats show increased granulopoiesis as well as increased erythropoiesis as compared with the spleen...

Journal: :Blood 1990
Y Sonoda T Okuda S Yokota T Maekawa Y Shizumi H Nishigaki S Misawa H Fujii T Abe

We studied the effects of recombinant human interleukin-4 (IL-4) on colony formation by enriched hematopoietic progenitors. IL-4 alone did not support colony formation at all. When IL-4 was combined with granulocyte colony-stimulating factor (G-CSF), the number of pure neutrophil colonies increased three times over that supported by G-CSF alone. IL-4 added 5 days after the addition of G-CSF fai...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000
D R Kuritzkes

Neutropenia frequently complicates infection due to human immunodeficiency virus (HIV). The etiology of neutropenia in this setting includes bone marrow infection or infiltration, myelosuppressive therapies, the presence of antibodies to HIV, and accelerated apoptosis. Protection against microbial invaders by neutrophils is further compromised by impaired chemotaxis and phagocytosis, production...

Journal: :Blood 1989
N Komatsu T Suda M Moroi N Tokuyama Y Sakata M Okada T Nishida Y Hirai T Sato A Fuse

Recently, a human megakaryoblastic cell line, CMK, was established from the peripheral blood of a megakaryoblastic leukemia patient with Down syndrome. Using this cell line, we studied the proliferation and differentiation of megakaryocytic cells in the presence of highly purified human hematopoietic factors and phorbol 12-myristate-13-acetate (PMA). In a methylcellulose culture system, interle...

Journal: :Acta dermato-venereologica 2007
Takeshi Nara Hanako Atsuta Naoto Koizumi Hideya Takenaka Norito Katoh Saburo Kishimoto

Sir, Squamous cell carcinoma (SCC) can occur anywhere on the skin and in mucous membranes with a squamous epithelium (1). Malignant tumours producing granulocyte colony-stimulating factor (G-CSF) have been reported in lung cancer, thyroid carcinoma, bladder carcinoma and cutaneous angiosarcoma (2). We encountered a case of G-CSF-producing SCC, which was diagnosed by immunohistochemical staining...

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