BACKGROUND Before performing spine non-fusion surgery that retains the facet joints, choosing an accurate radiographic method to evaluate the degree of facet joint degeneration is extremely important. Therefore, the objective of this study was to determine the accuracy and reliability of different radiographic classifications by analyzing the correlation between radiographic and pathologic grad...

Brain tumor is a mass that grows unevenly in the brain and directly affects human life. The occurs spontaneously because of tissues surrounding or skull. There are two types such as Benign Malignant. Malignant tumors contain cancer cells grow quickly spread through to other spine regions well. Accurate prompt diagnosis essential for implementing an effective treatment this disease. images produ...

Aberrant expression of miR-141 has recently implicated in the occurrence and development of various types of malignant tumors. However whether the involvement of miR-141 in the pathogenesis of glioma remains unknown. Here, we showed that miR-141 was markedly downregulated in glioma tissues and cell lines compared with normal brain tissues, and its expression correlated with the pathological gra...

In this paper a feasibility study of brain MRI dataset classification, using ROIs which have been segmented either manually or through a superpixel based method in conjunction with statistical pattern recognition methods is presented. In our study, 471 extracted ROIs from 21 Brain MRI datasets are used, in order to establish which features distinguish better between three grading classes. Thirt...

Brain tumor is one of the leading causes cancer-related death globally among children and adults. Precise classification brain grade (low-grade high-grade glioma) at an early stage plays a key role in successful prognosis treatment planning. With recent advances deep learning, artificial intelligence–enabled grading systems can assist radiologists interpretation medical images within seconds. T...

Abstract PURPOSE Since it is known that midline located glioma with H3K27 mutation in children has a disastrous prognosis, 2016 WHO classification, these tumors were defined as diffuse (DMG) and classified grade IV. A lot of papers about pediatric DMG have been published, but there are not many adult DMG. In this study, we aimed to identify factors affecting the prognosis glioma. This first pap...

BACKGROUND Diffusion kurtosis imaging (DKI) allows for assessment of diffusion influenced by microcellular structures. We analyzed DKI in suspected low-grade gliomas prior to histopathological diagnosis. The aim was to investigate if diffusion parameters in the perilesional normal-appearing white matter (NAWM) differed from contralesional white matter, and to investigate differences between gli...

Tumoral neoangiogenesis characterizes high grade gliomas. Relative Cerebral Blood Volume (rCBV), calculated with Dynamic Susceptibility Contrast (DSC) Perfusion-Weighted Imaging (PWI), allows for the estimation of vascular density over the tumor bed. The aim of the study was to characterize putative tumoral neoangiogenesis via the study of maximal rCBV with a Region of Interest (ROI) approach i...

BACKGROUND The extraordinary invasive capability is a major cause of treatment failure and tumor recurrence in glioma, however, the molecular and cellular mechanisms governing glioma invasion remain poorly understood. Evidence in other cell systems has implicated the regulatory role of microRNA in cell motility and invasion, which promotes us to investigate the biological functions of miR-124 i...

Human glioma, arising from glial cells of the central nervous system, accounts for almost 30%of all brain tumours , neoplasms with a poor prognosis and high mortality rates worldwide. In the present study we assessed tissue architectural modifications associated with macrophage lineage cells, controversial major immune effector cells within the brain, in human glioma tissue samples from eastern...