Protease inhibitors regulate a variety of physiological and pathological processes including angiogenesis, embryo implantation, intravascular fibrinolysis, wound healing, and tumor invasion. Tissue factor pathway inhibitor (TFPI) 2 is a Mr 32,000 Kunitz-type serine protease inhibitor that inhibits plasmin, trypsin, chymotrypsin, cathepsin G, and plasma kallikrein but not urokinase-type plasmino...

there is great interest worldwide in discovering and developing a permanent source of tissues which would be capable of generating any cell type and which would avoid the problem of transplant rejection. stem cells are cells that can specialize into the many different cells found in the human body. the ethical objections concerning stem cells have focused primarily on their source. human embryo...

Assisted human reproduction is characterized by a high variability in results regarding pregnancy and birth rates. In fact, in a cohort of fertilized oocytes from the same stimulation cycle, the development rate varies drastically, even though produced at the same time and under similar conditions. This variability results in large differences in implantation potential of human embryos develope...

The objective of this study was to estimate variance components for oocyte and embryo production traits in Guzerá breed female donors, and investigate their associations with age at first calving (AFC). The traits analyzed were the number of viable oocytes (NOV), the number of grade I oocytes (NGI), the number of cleaved embryos (NCLV), and viable embryos produced (NEMB), and the percentages of...

the major objective of seedless grape breeding program is production of grapes with high quality. breeding of seedless grapes is difficult because the embryos are aborted after fertilization. embryo rescue technique is utilized to obtain plants from crosses between seedless cultivars. in the present study, the effect of paternal genotypes and different iaa concentrations in presence of ba appli...

the aim of this study was to analyze the incidence of stage of embryonic development, embryo quality and the time of transfer on pregnancy rate in embryo transfer program timed. we were worked a total of 23holsteincowsasembryo donors, super-ovulated with gonadotropin of pregnant mare serum (pmsg) (2500 3000ui).69 cows were used as recipients of holstein dairy heifers with an age of20 months and...

objective: after the introduction of assisted reproductive techniques, human embryos were officially introduced into laboratories and now thousands of them are cryopreserved in such settings. embryonic stem cells and the future application of such cells in the treatment of disease opened the door to further research on human embryos. these developments raise many ethical issues, some of which h...